F8384

Flavin adenine dinucleotide disodium salt hydrate

suitable for cell culture, BioReagent

• Synonyme(s) : FAD, FAD-Na₂, Riboflavin 5′-adenosine diphosphate disodium salt
• Formule empirique (notation de Hill) : C₂₇H₃₁N₉Na₂O₁₅P₂ · xH₂O
• Numéro CAS: 84366-81-4
• Poids moléculaire : 829.51 (anhydrous basis)
• UNSPSC Code: 12352207
• NACRES: NA.75
• PubChem Substance ID: 24894962
• MDL number: MFCD08277021
• Beilstein/REAXYS Number: 5326842
• Form: powder
• Assay: ≥95%
• Solubility: water: 50 mg/mL, clear
• Biological source: bovine milk

Propriétés

• biological source: bovine milk
• Quality Segment: 200
• product line: BioReagent
• assay: ≥95%
• form: powder
• technique(s): cell culture | mammalian: suitable
• solubility: water: 50 mg/mL, clear
• storage temp.: −20°C
• SMILES string: [Na+].[Na+].[H]O[H].Cc1cc2N=C3C(=O)NC(=O)N=C3N(C[C@H](O)[C@H](O)[C@H](O)COP([O-])(=O)OP([O-])(=O)OC[C@H]4O[C@H]([C@H](O)[C@@H]4O)n5cnc6c(N)ncnc56)c2cc1C
• InChI: 1S/C27H33N9O15P2.2Na.H2O/c1-10-3-12-13(4-11(10)2)35(24-18(32-12)25(42)34-27(43)33-24)5-14(37)19(39)15(38)6-48-52(44,45)51-53(46,47)49-7-16-20(40)21(41)26(50-16)36-9-31-17-22(28)29-8-30-23(17)36;;;/h3-4,8-9,14-16,19-21,26,37-41H,5-7H2,1-2H3,(H,44,45)(H,46,47)(H2,28,29,30)(H,34,42,43);;;1H2/q;2*+1;/p-2/t14-,15+,16+,19-,20+,21+,26+;;;/m0.../s1
• InChI key: GXTPHHZYFMAGLX-UJXBNFGUSA-L

Description

General description

Flavin adenine dinucleotide (FAD) is a redox cofactor of flavoproteins, such as cytochrome-b₅ reductase enzyme. With the help of nicotinamide adenine dinucleotide phosphate (NADPH), FAD can be reduced to form FADH₂.

Application

Flavin adenine dinucleotide disodium salt hydrate has been used as a component in the extraction buffer for plant tissue extraction. It has also been used to study its effects on infarct areas of middle cerebral artery occlusion (MCAO) induced mice.

Flavin adenine dinucleotide (FAD) is used as a redox cofactor (electron carrier) by flavoproteins including succinate dehydrogenase (complex), α-ketoglutarate dehydrogenase, apoptosis-inducing factor 2 (AIF-M2, AMID), folate/FAD-dependent tRNA methyltransferases, and N-hydroxylating flavoprotein monooxygenases. FAD is a component of the pyruvate dehydrogenase complex.

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)