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A propos de cet article
Formule empirique (notation de Hill) :
C20H21FN2O · HBr
Numéro CAS:
Poids moléculaire :
405.30
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
261-890-6
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Service technique
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Laissez-nous vous aiderNom du produit
Citalopram hydrobromide, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
powder
solubility
chloroform: soluble, methanol: soluble
originator
Forest Labs
storage temp.
2-8°C
SMILES string
Br[H].CN(C)CCCC1(OCc2cc(ccc12)C#N)c3ccc(F)cc3
InChI
1S/C20H21FN2O.BrH/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20;/h4-9,12H,3,10-11,14H2,1-2H3;1H
InChI key
WIHMBLDNRMIGDW-UHFFFAOYSA-N
Gene Information
General description
Citalopram is a bicyclic phthalene derivative. It initiates serotonergic activity, which produces antidepressant action. Citalopram hydrobromide reverses memory impairment. It is used to treat obsessive compulsive disorder, panic disorder, sociophobia and premenstrual dysphoric disorder.
Application
Citalopram hydrobromide has been used:
- to examine its effects on sirt mRNA and mammalian sirtuins (SIRT) expression in mice
- to monitor body temperature and antidepressant-like behavioral responses in the forced swim test for rats
- for 5-hydroxytryptamine (5-HT) competition uptake assays
Biochem/physiol Actions
Potent and selective serotonin uptake inhibitor (Ki = 5.4 nM); antidepressant
Features and Benefits
This compound was developed by Forest Labs. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 3 - Repr. 2 - STOT SE 3
target_organs
Central nervous system
Classe de stockage
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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