C6240

CITCO

≥98% (HPLC), androstane receptor agonist, solid

• Synonyme(s) : 6-(4-Chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime
• Formule empirique (notation de Hill) : C₁₉H₁₂N₃OCl₃S
• Numéro CAS: 338404-52-7
• Poids moléculaire : 436.74
• UNSPSC Code: 12352203
• PubChem Substance ID: 24724448
• NACRES: NA.77
• MDL number: MFCD00139608
• Assay: ≥98% (HPLC)
• Form: solid
• Storage condition: desiccated

Propriétés

• Nom du produit: CITCO, ≥98% (HPLC), solid
• Quality Segment: 200
• assay: ≥98% (HPLC)
• form: solid
• storage condition: desiccated
• solubility: DMSO: soluble 28 mg/mL, H₂O: insoluble
• storage temp.: −20°C
• SMILES string: Clc1ccc(cc1)-c2nc3sccn3c2\C=N\OCc4ccc(Cl)c(Cl)c4
• InChI: 1S/C19H12Cl3N3OS/c20-14-4-2-13(3-5-14)18-17(25-7-8-27-19(25)24-18)10-23-26-11-12-1-6-15(21)16(22)9-12/h1-10H,11H2/b23-10+
• InChI key: ZQWBOKJVVYNKTL-AUEPDCJTSA-N

Description

General description

CITCO is an imidazothiazole derivative. It stimulates human constitutive androstane receptor (CAR) nuclear translocation.

Application

CITCO has been used for the activation of mouse constitutive androstane receptor (CAR) and human CAR.

Biochem/physiol Actions

CITCO is a constitutive androstane receptor (CAR) agonist; nuclear receptor NR113 agonist.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mot-clé: Warning
• Codes de danger: H315,H319,H335
• Mentions de précaution: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Classe de stockage: 11 - Combustible Solids
• Que se passe-t-il ?: WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• EPI (équipement de protection individuelle): dust mask type N95 (US), Eyeshields, Gloves