B2417

Benzamil hydrochloride hydrate

≥98% (HPLC), ENaC and NCX inhibitor, solid

• Synonyme(s) : N-(Benzylamidino)-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride hydrate
• Formule empirique (notation de Hill) : C₁₃H₁₄ClN₇O · HCl · xH₂O
• Numéro CAS: 161804-20-2
• Poids moléculaire : 356.21 (anhydrous basis)
• MDL number: MFCD28147597
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278262
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: solid
• Storage condition: desiccated

Propriétés

• Nom du produit: Benzamil hydrochloride hydrate, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: solid
• storage condition: desiccated
• color: yellow
• solubility: methanol: 10 mg/mL, DMSO: >20 mg/mL
• storage temp.: 2-8°C
• SMILES string: O.Cl.Nc1nc(N)c(nc1Cl)C(=O)NC(=N)NCc2ccccc2
• InChI: 1S/C13H14ClN7O.ClH.H2O/c14-9-11(16)20-10(15)8(19-9)12(22)21-13(17)18-6-7-4-2-1-3-5-7;;/h1-5H,6H2,(H4,15,16,20)(H3,17,18,21,22);1H;1H2
• InChI key: YAJQRPFIYXRNKS-UHFFFAOYSA-N
• Gene Information: human ... SCNN1A(6337), SCNN1B(6338), SCNN1D(6339), SCNN1G(6340) ; mouse ... Scnn1a(20276), Scnn1b(20277), Scnn1d(140501), Scnn1g(20278) ; rat ... Scnn1a(25122), Scnn1b(24767), Scnn1g(24768)

Description

Biochem/physiol Actions

Selective and potent blocker of Na⁺/H⁺ and Na⁺/Ca²⁺ channels

Features and Benefits

This compound is featured on the Acid-Sensing (Proton-gated) Ion Channels (ASICs) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Other Notes

N_ω-Benzyl derivative of amiloride.

Informations sur la sécurité

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves