A3286

N-Acétyl-D-glucosamine

BioReagent, suitable for cell culture

• Synonyme(s) : 2-Acétamido-2-désoxy-D-glucose, D-GlcNAc
• Formule empirique (notation de Hill): C₈H₁₅NO₆
• Numéro CAS: 7512-17-6
• Poids moléculaire : 221.21
• Numéro Beilstein : 1727589
• Numéro CE : 231-368-2
• Numéro MDL: MFCD00061615
• Code UNSPSC : 12352201
• ID de substance PubChem : 24890757
• Nomenclature NACRES : NA.75

Propriétés

• Gamme de produits: BioReagent
• Pureté: ≥95% (HPLC)
• Forme: powder
• Technique(s): cell culture | mammalian: suitable
• Pf: 211 °C (dec.) (lit.)
• Température de stockage: −20°C
• Chaîne SMILES: CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O
• InChI: 1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6-,7-,8?/m1/s1
• Clé InChI: OVRNDRQMDRJTHS-RTRLPJTCSA-N

Description

Description générale

N-Acetylglucosamine (GlcNAc), a derivative of glucose is a monosaccharide. It is a white powder and is mildly sweet. It melts at 221°C. GlcNAc is 25% soluble in water. It is present in bromelain, ricin agglutinin and abrus agglutinin, in plants. In humans, it is present in tissue plasminogen activator, growth factors and hormones.

Application

N-Acetyl-D-glucosamine addition has been used:

• as a substrate to develop dot-blots
• as a substrate to reveal alkaline phosphatase in the immunohistochemical analysis
• to detect specific immune complexes in western blot analysis

Actions biochimiques/physiologiques

N-Acetylglucosamine (GlcNAc) oligomer may have the ability to initiate factors for canine polymorphonuclear cells (PMN) in vivo. It possesses wound healing and chemotactic activity. GlcNAc and its derivatives are usually employed in preparing dietary supplements and also used in therapeutic development.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)