S2255

Safranine O

Dye content ≥85 %, Powder

• Synonyme(s) : Cotton Red, Basic Red 2, Gossypimine, Safranine T, Safranine Y ou A
• Formule empirique (notation de Hill) : C₂₀H₁₉ClN₄
• Numéro CAS: 477-73-6
• Poids moléculaire : 350.84
• UNSPSC Code: 12171500
• NACRES: NA.47
• PubChem Substance ID: 24899516
• EC Number: 207-518-8
• MDL number: MFCD00011759
• Colour Index Number: 50240
• Beilstein/REAXYS Number: 3924099

Propriétés

• Nom du produit: Safranine O, Dye content ≥85 %
• form: powder
• Quality Segment: 200
• composition: Dye content, ≥85%
• technique(s): microbe id | staining: suitable
• pH: 10 (20 °C, 10 g/L)
• solubility: water: 1 mg/mL, clear, dark red to very dark red and red purple
• εmax: 1250-1650 at 530-534 nm in 50% ethanol
• application(s): diagnostic assay manufacturing; hematology; histology
• storage temp.: room temp
• SMILES string: [Cl-].Cc1cc2nc3cc(C)c(N)cc3[n+](-c4ccccc4)c2cc1N
• InChI: 1S/C20H18N4.ClH/c1-12-8-17-19(10-15(12)21)24(14-6-4-3-5-7-14)20-11-16(22)13(2)9-18(20)23-17;/h3-11H,1-2H3,(H3,21,22);1H
• InChI key: OARRHUQTFTUEOS-UHFFFAOYSA-N

Description

General description

Safranin O is a cationic dye, which displays less significant metachromasia. It is used to detect any variations in articular disease. Safranin O binds specifically to polyanions. It detects the amount of proteoglycan present in cartilages. Safranin O is used as a marker for glycosaminoglycan depletion in osteoarthritis. Safranin is used as a counter stain in Gram staining.

Application

Safranin O has been used in the histological analysis of femurs. It has also been used to detect the presence of glycosaminoglycans in the inner body of meniscus structures.

Informations sur la sécurité

• pictograms: GHS05
• signalword: Danger
• hcodes: H318
• pcodes: P280 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1
• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• ppe: dust mask type N95 (US), Eyeshields, Gloves