BP333

Tobramycine

British Pharmacopoeia (BP) Reference Standard

• Synonyme(s) : Nébramycine (facteur 6), O-[3-Amino-3-déoxy-α-D-glucopyranosyl-(1→6)]-O-[2,6-diamino-2,3,6-tridéoxy-α-D-ribohexopyranosyl-(1→4)]-2-déoxy-D-streptamine
• Formule empirique (notation de Hill) : C₁₈H₃₇N₅O₉
• Numéro CAS: 32986-56-4
• Poids moléculaire : 467.51
• NACRES: NA.24
• UNSPSC Code: 41116107
• Beilstein/REAXYS Number: 1357507
• MDL number: MFCD00077885
• eCl@ss: 25140904

Propriétés

• grade: pharmaceutical primary standard
• API family: tobramycin
• form: solid
• shelf life: limited shelf life, expiry date on the label
• manufacturer/tradename: BP
• application(s): pharmaceutical; pharmaceutical small molecule
• format: neat
• storage temp.: 2-8°C
• SMILES string: NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O
• InChI: 1S/C18H37N5O9/c19-3-9-8(25)2-7(22)17(29-9)31-15-5(20)1-6(21)16(14(15)28)32-18-13(27)11(23)12(26)10(4-24)30-18/h5-18,24-28H,1-4,19-23H2/t5-,6+,7+,8-,9+,10+,11+,12+,13+,14-,15+,16-,17+,18+/m0/s1
• InChI key: NLVFBUXFDBBNBW-SNGYORCQSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support

Application

Tobramycin BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Tobramycin and Dexamethasone Eye Drops, Suspension

Apramycin Premix

Tobramycin Inhalation Powder, Hard Capsule

Apramycin Sulfate

Tobramycin Nebuliser Solution

Tobramycin Oral Solution

Tobramycin Eye Drops

Tobramycin Injection

Tobramycin Sulfate

Apramycin Veterinary Oral Powder

Biochem/physiol Actions

La tobramycine est un aminoglycoside.
Mode d′action : Se lie à la sous-unité ribosomale 70S ; inhibe la translocation ; provoque des erreurs d′encodage.
Spectre d′activité : bactéries à Gram négatif. Non efficace contre les Enterococci.

Packaging

Unit quantity: 350 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Other Notes

Sales restrictions may apply.

Informations sur la sécurité

• Pictogrammes: GHS08
• Mot-clé: Warning
• Codes de danger: H361f
• Mentions de précaution: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 2
• Classe de stockage: 11 - Combustible Solids