46648

Praziquantel

VETRANAL^®, analytical standard

• Synonyme(s) : 2-(Cyclohexylcarbonyl)-1,2,3,6,7-11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one
• Formule empirique (notation de Hill) : C₁₉H₂₄N₂O₂
• Numéro CAS: 55268-74-1
• Poids moléculaire : 312.41
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329756613
• EC Number: 259-559-6
• Beilstein/REAXYS Number: 761557
• MDL number: MFCD00058531

Propriétés

• grade: analytical standard
• Quality Segment: 200
• product line: VETRANAL^®
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable, chromatography: suitable, gas chromatography (GC): suitable
• antibiotic activity spectrum: parasites
• application(s): clinical testing
• format: neat
• mode of action: cell membrane | interferes
• storage temp.: 2-8°C
• SMILES string: O=C1CN(CC2N1CCc3ccccc23)C(=O)C4CCCCC4
• InChI: 1S/C19H24N2O2/c22-18-13-20(19(23)15-7-2-1-3-8-15)12-17-16-9-5-4-6-14(16)10-11-21(17)18/h4-6,9,15,17H,1-3,7-8,10-13H2
• InChI key: FSVJFNAIGNNGKK-UHFFFAOYSA-N

Description

General description

Praziquantel (PZQ) is a pyrazino-isoquinoline compound used as a broad-spectrum anthelmintic drug against trematode and cestode infections.

Chemical structure: quinolone

Application

PZQ may be used as a reference standard for the determination for PZQ in:

• Surface water samples by solid phase extraction (SPE) and ultra-high performance liquid chromatography-quadrupole linear ion trap tandem mass spectrometry (UHPLC-QqLIT-MS) equipped with electrospray ionization (ESI) source.
• Plants by HPLC with triple quadrupole mass spectrometry (HPLC-ESI-QqQ-MS/MS) operating in multiple reaction monitoring (MRM) mode.
• Tablet formulations by reversed phase (RP) HPLC with ultraviolet (UV) detection.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Codes de danger: H412
• Mentions de précaution: P273 - P501
• Hazard Classifications: Aquatic Chronic 3
• Classe de stockage: 11 - Combustible Solids
• Que se passe-t-il ?: WGK 1
• EPI (équipement de protection individuelle): Eyeshields, Gloves, type N95 (US)