14510

1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid

≥96.0% (HPLC)

• Synonyme(s) : BAPTA, Ethylenedioxybis(o-phenylenenitrilo)tetraacetic acid
• Formule empirique (notation de Hill) : C₂₂H₂₄N₂O₁₀
• Numéro CAS: 85233-19-8
• Poids moléculaire : 476.43
• UNSPSC Code: 12352112
• NACRES: NA.22
• PubChem Substance ID: 329750514
• MDL number: MFCD00036255
• Beilstein/REAXYS Number: 5192406
• Assay: ≥96.0% (HPLC)
• Form: powder

Propriétés

• Quality Segment: 200
• assay: ≥96.0% (HPLC)
• form: powder
• fluorescence: λ_ex 251 nm; λ_em 363 nm, λ_ex 274 nm; λ_em 363 nm (With Calcium)
• functional group: amine, carboxylic acid
• storage temp.: 2-8°C
• SMILES string: OC(=O)CN(CC(O)=O)c1ccccc1OCCOc2ccccc2N(CC(O)=O)CC(O)=O
• InChI: 1S/C22H24N2O10/c25-19(26)11-23(12-20(27)28)15-5-1-3-7-17(15)33-9-10-34-18-8-4-2-6-16(18)24(13-21(29)30)14-22(31)32/h1-8H,9-14H2,(H,25,26)(H,27,28)(H,29,30)(H,31,32)
• InChI key: FTEDXVNDVHYDQW-UHFFFAOYSA-N

Description

General description

1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid is a highly selective calcium chelating reagent. Effect of microinjected calcium-loaded 1,2-bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid (CaBAPTA) on cell-to-cell diffusion of carboxyfluorescein has been studied in staminal hairs of Setcreasea purpurea. It is reported to be a metabolite of 1,2-bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid tetra(acetoxymethyl ester) (BAPTA-AM) in rat urine.

pH 8.0 Highly selective calcium chelating reagent. Suitable for the spectrophotometric monitoring of Ca2+ levels

Application

1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′′-tetraacetic acid was used for the spectrophotometric monitoring of Ca²⁺ levels. It may be used as chelator of cytosolic Ca²⁺ to investigate the effect of methoxychlor on cytosolic free Ca²⁺ concentrations and apoptosis in HA59T human hepatoma cells.

Highly selective calcium chelating reagent. Suitable for the spectrophotometric monitoring of Ca²⁺ levels

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• Que se passe-t-il ?: WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• EPI (équipement de protection individuelle): dust mask type N95 (US), Eyeshields, Gloves