GF171

Endostatin Protein, Human Recombinant

The Endostatin protein is a naturally occurring 20 kDa polypeptide derived from the C-terminal portion of type XVIII collagen.

• Synonyme(s) : Collagen Type XVIII, Collagen alpha-1 (XVIII)
• UNSPSC Code: 12352202
• NACRES: NA.75
• eCl@ss: 32160405
• Assay: >98% (SDS-PAGE and HPLC)
• Recombinant: expressed in E. coli

Propriétés

• recombinant: expressed in E. coli
• Quality Segment: 100
• assay: >98% (SDS-PAGE and HPLC)
• impurities: <0.1 μg/mg protein endotoxin (<1EU/μg)
• UniProt accession no.: P39060
• shipped in: dry ice

Description

General description

Endostatin is a naturally occurring 20 kDa polypeptide derived from the C-terminal portion of type XVIII collagen. It functions as an anti-angiogenic cytokine that is expressed in various organs with the highest levels in liver, lung and kidney. Endostatin inhibits angiogenesis by blocking the pro-angiogenic activities of VEGF and FGF-basic. Recombinant human Endostatin is a 20.2 kDa protein consisting 184 amino acid residues.

Product Source: E. coli.

Application

Research Category
Stem Cell Research

Research Sub Category
Growth Factors & Receptors

Biochem/physiol Actions

Cross Reactivty
None

Physical form

Product is filtered through a 0.2 micron filter before lyophilization.

Preparation Note

Store at -20°C for up to 6 months from date of receipt.

Analysis Note

Bioactivity assay: Measured by its ability to inhibit HUVEC migration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• Que se passe-t-il ?: WGK 1