CBL468
Anti-PECAM-1 Antibody, domains 3-6 of human PECAM-1, clone HC1/6
clone HC1/6, Chemicon®, from mouse
Synonyme(s) :
CD31
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About This Item
Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41
Produits recommandés
Source biologique
mouse
Niveau de qualité
Forme d'anticorps
purified immunoglobulin
Clone
HC1/6, monoclonal
Espèces réactives
human
Fabricant/nom de marque
Chemicon®
Technique(s)
flow cytometry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
immunoprecipitation (IP): suitable
Isotype
IgG1
Numéro d'accès NCBI
Numéro d'accès UniProt
Conditions d'expédition
wet ice
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
human ... PECAM1(5175)
Spécificité
Reacts with a 130-140 kDa transmembranous glycoprotein that is expressed widely amongst cells of the vascular compartment. CD31 is expressed on platelets, cultured endothelial cells, monocytes, normal tissue macrophages in tonsil, lung and kidney as well as in skin biopsies from conditions such as sarcoidosis and lepromatous leprosy.
FUSION PARTNER: P3-x63Ag8.653 myeloma cell line
FUSION PARTNER: P3-x63Ag8.653 myeloma cell line
Immunogène
Epitope: domains 3-6 of human PECAM-1
Application
Anti-PECAM-1 Antibody, domains 3-6 of human PECAM-1, clone HC1/6 is an antibody against PECAM-1 for use in FC, IH, IH(P) & IP.
Studies of the role of CD31 in leucocyte migration into inflammatory sites and in the process of angiogenesis
This antibody will stain frozen tissue sections
Suitable for immunoprecipitation studies
Suitable for flow cytometry either indirectly or directly when labelled with FITC or R-PE
Suitable for use on formalin fixed paraffin embedded sections after protease pre-treatment.
Optimal working dilutions must be determined by the end user.
This antibody will stain frozen tissue sections
Suitable for immunoprecipitation studies
Suitable for flow cytometry either indirectly or directly when labelled with FITC or R-PE
Suitable for use on formalin fixed paraffin embedded sections after protease pre-treatment.
Optimal working dilutions must be determined by the end user.
Forme physique
Format: Purified
Remarque sur l'analyse
Control
Activated microglial cells
Activated microglial cells
Autres remarques
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Informations légales
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
En option
Réf. du produit
Description
Tarif
Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
WGK 2
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Guiting Lin et al.
Stem cells and development, 17(6), 1053-1063 (2008-07-04)
Adipose tissue-derived stem cells (ADSC) are routinely isolated from the stromal vascular fraction (SVF) of homogenized adipose tissue. Freshly isolated ADSC display surface markers that differ from those of cultured ADSC, but both cell preparations are capable of multipotential differentiation.
Yu-Ting Huang et al.
Cellular signalling, 20(8), 1521-1527 (2008-05-27)
Sphingosine 1-phosphate (S1P) is a multifunctional phospholipid which acts through a specific family of G protein-coupled receptors. Platelet/endothelial cell adhesion molecule-1 (PECAM-1) form trans-homophilic binding at lateral cell border. Upon stimulation, its cytoplasmic tyrosine residues could be phosphorylated and interact
Fumiko Obata et al.
Toxins, 14(2) (2022-02-25)
Shiga toxin-producing Escherichia coli (STEC) causes proximal tubular defects in the kidney. However, factors altered by Shiga toxin (Stx) within the proximal tubules are yet to be shown. We determined Stx receptor Gb3 in murine and human kidneys and confirmed
Gina Lisignoli et al.
Journal of cellular physiology, 220(2), 401-409 (2009-04-15)
Bone marrow stromal cells (MSCs) and osteoblasts are the two main non-haematopoietic cellular components of human bone tissue. To identify novel osteoblast-related molecules, we performed a gene expression profiling analysis comparing MSCs and osteoblasts isolated from the same donors. Genes
T M Herndon et al.
Journal of immunology (Baltimore, Md. : 1950), 166(9), 5654-5664 (2001-04-21)
The transcription factor NF-kappaB is a critical regulator of T cell function that becomes strongly activated in response to coengagement of TCR and CD28. Although events immediately proximal to NF-kappaB activation are well understood, uncertainty remains over which upstream signaling
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