8.52030

Fmoc-Thr-OH

Novabiochem^®

• Synonyme(s) : Fmoc-Thr-OH, N-α-Fmoc-L-threonine
• Formule empirique (notation de Hill) : C₁₉H₁₉NO₅
• Numéro CAS: 73731-37-0
• Poids moléculaire : 341.36
• UNSPSC Code: 12352209
• NACRES: NA.22
• MDL number: MFCD00792901

Propriétés

• Quality Segment: 200
• product line: Novabiochem^®
• assay: ≥93.0% (acidimetric), ≥98% (TLC), ≥98.0% (HPLC)
• form: powder
• reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
• manufacturer/tradename: Novabiochem^®
• mp: 90-100 °C
• application(s): peptide synthesis
• functional group: hydroxyl
• storage temp.: 2-30°C
• SMILES string: N([C@@H]([C@@H](O)C)C(=O)[O-])C(=O)OCC1c2c(cccc2)c3c1cccc3
• InChI: 1S/C19H19NO5/c1-11(21)17(18(22)23)20-19(24)25-10-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,11,16-17,21H,10H2,1H3,(H,20,24)(H,22,23)/p-1/t11-,17-/m0/s1
• InChI key: OYULCCKKLJPNPU-GTNSWQLSSA-M

Description

General description

Useful derivative for the synthesis of phosphothreonine peptides by the Fmoc SPPS global phosphorylation methodology.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS


Literature references

^[1] P. M. Fischer, et al. (1991) Int. J. Peptide Protein Res., 38, 491

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(011C)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 93.0 %
Water (K. F.): ≤ 6.00 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Other Notes

Replaces: 04-12-1060

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• Que se passe-t-il ?: WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable