8.08259

2,2,2-Trifluoroethanol

for synthesis

• Synonyme(s) : 2,2,2-Trifluoroethanol
• Formule empirique (notation de Hill) : C₂H₃F₃O
• Numéro CAS: 75-89-8
• Poids moléculaire : 100.04
• UNSPSC Code: 12352104
• EC Index Number: 200-913-6
• NACRES: NA.22
• MDL number: MFCD00004672
• Assay: ≥99% (GC)
• Grade: synthesis grade
• Bp: 73.6 °C/1013 hPa
• Vapor pressure: 70.9 hPa ( 20 °C)

Propriétés

• grade: synthesis grade
• Quality Segment: 200
• vapor pressure: 70.9 hPa ( 20 °C)
• assay: ≥99% (GC)
• form: liquid
• potency: 240 mg/kg LD₅₀, oral (Rat), 1680 mg/kg LD₅₀, skin (Rat)
• expl. lim.: 8.4-28.8 % (v/v)
• dilution: (for synthesis)
• pH: 7
• bp: 73.6 °C/1013 hPa
• mp: -43.5 °C
• transition temp: flash point 30 °C
• density: 1.38 g/cm³ at 25 °C
• storage temp.: 2-30°C
• SMILES string: FC(F)(F)CO
• InChI: 1S/C2H3F3O/c3-2(4,5)1-6/h6H,1H2
• InChI key: RHQDFWAXVIIEBN-UHFFFAOYSA-N

Description

General description

2,2,2-Trifluoroethanol (TFE) is a fluorinated compound used as a solvent in organic synthesis. Peptides and proteins are experimentally studied using TEE as a cosolvent. In TFE, hydrogen peroxide is effective for oxidizing sulfur compounds.

Application

2,2,2-Trifluoroethanol is used as a solvent:

• In the preparation of nylon/Ag composite nanofibers by electrospinning method.
• To study the combination of two polymers PANI (polyaniline) and PHB (polyhydroxy-butyrate).

Features and Benefits

2,2,2-Trifluoroethanol is more acidic than ethanol due to the presence of electronegative trifluoromethyl group.

Informations sur la sécurité

• Mot-clé: Danger
• Mentions de précaution: P202 - P210 - P280 - P301 + P310 - P304 + P340 + P311 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1 - Flam. Liq. 3 - Repr. 1B - STOT RE 2 Inhalation
• Organes cibles: Blood
• Classe de stockage: 3 - Flammable liquids
• Que se passe-t-il ?: WGK 1
• Point d'éclair (°F): 86.0 °F - closed cup
• Point d'éclair (°C): 30 °C - closed cup
• Pictogrammes: GHS02,GHS06,GHS08,GHS05
• Codes de danger: H226,H301 + H331,H318,H360F,H373