444244

MMP-2 Inhibitor I

The MMP-2 Inhibitor I, also referenced under CAS 10335-69-0, controls the biological activity of MMP-2. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

• Synonyme(s) : MMP-2 Inhibitor I, cis-9-Octadecenoyl-N-hydroxylamide, Oleoyl-N-hydroxylamide, OA-Hy
• Formule empirique (notation de Hill) : C₁₈H₃₅NO₂
• Numéro CAS: 10335-69-0
• Poids moléculaire : 297.48
• MDL number: MFCD02683956
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: solid
• Storage condition: OK to freeze, protect from light

Propriétés

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: solid
• potency: 1.7 mM K_i
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, protect from light
• color: white
• solubility: DMSO: 2 mg/mL, ethanol: 3 mg/mL
• shipped in: wet ice
• storage temp.: −20°C
• SMILES string: N(O)C(=O)CCCCCCC\C=C/CCCCCCCC
• InChI: 1S/C18H35NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(20)19-21/h9-10,21H,2-8,11-17H2,1H3,(H,19,20)/b10-9-
• InChI key: LTXHELLMCCEDJG-KTKRTIGZSA-N

Description

General description

A cell-permeable, potent inhibitor of MMP-2 that acts in a dose-dependent manner (K_i = 1.7 µM).

Potent inhibitor of MMP-2 (gelatinase A). Inhibits MMP-2 in a dose dependent manner (K_i = 1.7 µM)

Biochem/physiol Actions

Cell permeable: yes

Primary Target
MMP-2

Product does not compete with ATP.

Reversible: no

Packaging

Packaged under inert gas

Preparation Note

Unstable in solution; reconstitute just prior to use.

Other Notes

Berton, A., et. al. 2001. J. Biol. Chem.276, 20458.
Emonard, H., et al. 1999. Ann. N.Y. Acad. Sci.878, 647.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• Que se passe-t-il ?: WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable