238470
Cremophor® EL
Synonyme(s) :
Castor oil polyoxyethylene ether, Ethoxylated castor oil, PEG-35 castor oil, Polyoxyl 35 castor oil, polyoxyl 35 castor oil
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liquid
Quality Segment
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
clear pale yellow
CMC
~0.02%
solubility
ethanol: soluble, water: soluble, clear (at higher temperatures the solution will be come turbid)
density
1,050 g/cm3
application(s)
(Excipient in drug)
shipped in
ambient
storage temp.
2-8°C
SMILES string
ClCC(OC(=O)N)CCl
InChI
1S/C4H7Cl2NO2/c5-1-3(2-6)9-4(7)8/h3H,1-2H2,(H2,7,8)
InChI key
JMNCUXPHXKHBPY-UHFFFAOYSA-N
General description
1 Set = 5 X 25 GM
A mixture of polyoxyethylated triglycerides, by reacting castor oil with ethylene oxide in a molar ratio of 1 : 35, that acts as a nonionic surfactant and serves as a formulation vehicle (p.o. and i.v. administration) for poorly-water soluble pharmacological agents.
Hydrophilic-lipophilic balance (HLB) ~ 12 - 14.
Application
- Proteomic responses of carotenoid and retinol administration to Mongolian gerbils.: This research examines the proteomic responses in Mongolian gerbils administered with carotenoids and retinol. Cremophor® EL is utilized as a solubilizing agent for these compounds, highlighting its role in biochemical studies involving lipid-soluble substances (Bohn et al., 2018).
Packaging
Packaged under inert gas
Other Notes
Gelderblom, H., et al. 2001. Eur. J. Cancer37, 1590.
Sparreboom, A., et al. 1996. Cancer Res.56, 2112.
Woodcock, D.M., et al. 1990. Cancer Res.50, 4199.
Sparreboom, A., et al. 1996. Cancer Res.56, 2112.
Woodcock, D.M., et al. 1990. Cancer Res.50, 4199.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Cremophor is a registered trademark of BASF SE
Disclaimer
Toxicity: Standard Handling (A)
Classe de stockage
10 - Combustible liquids
Point d'éclair (°F)
494.6 °F - Not applicable
Point d'éclair (°C)
257 °C - Not applicable
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