229101

Cholic Acid, Sodium Salt

Primary bile acid.

• Synonyme(s) : Cholic Acid, Sodium Salt
• Formule empirique (notation de Hill) : C₂₄H₃₉O₅ · Na
• Numéro CAS: 361-09-1
• Poids moléculaire : 430.55
• MDL number: MFCD00077281
• UNSPSC Code: 12352106
• NACRES: NA.25
• Assay: >96% (TLC)
• Form: solid

Propriétés

• description: Merck USA index - 14, 2203
• Quality Segment: 200
• assay: >96% (TLC)
• form: solid
• mol wt: micellar wt 900
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, desiccated (hygroscopic)
• color: white
• pKa: 5.2
• CMC: 9 - 15 mM
• solubility: acetic acid: 1 mg/mL, ethanol: 1 mg/mL
• shipped in: ambient
• storage temp.: 15-25°C
• SMILES string: [Na+].[O-]C(=O)CC[C@H]([C@@H]1[C@@]2([C@H]([C@H]3[C@@H]([C@@]4([C@H](C[C@H]3O)C[C@@H](CC4)O)C)C[C@@H]2O)CC1)C)C
• InChI: 1S/C24H40O5.Na/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26;/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29);/q;+1/p-1/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-;/m1./s1
• InChI key: NRHMKIHPTBHXPF-TUJRSCDTSA-M

Description

General description

Primary bile acid.

Application

• EXPLOITING THE VERSATILITY OF CHOLESTEROL IN NANOPARTICLES FORMULATION.: This study explores the utility of cholic acid sodium salt in formulating nanoparticles with enhanced functionality for targeted drug delivery systems (Ruozi et al., 2016).


• Comparative study on the enantiomer separation of 1,1′-binaphthyl-2,2′diyl hydrogenphosphate and 1,1′-bi-2-naphthol by liquid chromatography and capillary electrophoresis using single and combined chiral selector systems.: Explores the role of cholic acid sodium salt in improving the efficiency of chiral separation techniques, vital for the development of pharmaceutical agents (Sybilska et al., 2002).

Preparation Note

Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 6 months at 4°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Informations sur la sécurité

• hcodes: H412
• pcodes: P273 - P501
• Hazard Classifications: Aquatic Chronic 3
• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable