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Merck

05-533

Anti-phospho-CaM Kinase II Antibody, α subunit, (Thr286), clone 22B1

clone 22B1, Upstate®, from mouse

Synonyme(s) :

Anti-Anti-CAMKA, Anti-Anti-CaMKIINalpha, Anti-Anti-CaMKIIalpha, Anti-Anti-MRD53, Anti-Anti-MRT63

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A propos de cet article

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
22B1, monoclonal
Species reactivity:
rat
Application:
WB
Citations:
15
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biological source

mouse

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

22B1, monoclonal

species reactivity

rat

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

phosphorylation (pThr286)

Gene Information

human ... CAMK2A(815)

General description

50kDa

Immunogen

Peptide corresponding to residuues 281-294 of rat Cam Kinase II alpha-subunit; recognizes phosphorylated CaM Kinase II on Threonine 286

Application

Detect phospho-CaM Kinase II using this Anti-phospho-CaM Kinase II Antibody, α subunit, (Thr286), clone 22B1 validated for use in WB.

Biochem/physiol Actions

phospho-CaM Kinase II α subunit

Physical form

Format: Purified

Analysis Note

routinely evaluated by immunoblot on rat brain microsomal protein preparation

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany


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WGK 1



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Overexpression of calbindin-D28K in hippocampal progenitor cells increases neuronal differentiation and neurite outgrowth.
Kim, JH; Lee, JA; Song, YM; Park, CH; Hwang, SJ; Kim, YS; Kaang, BK; Son, H
Faseb Journal null
Su-Ying Cui et al.
Journal of neurochemistry, 136(3), 609-619 (2015-11-13)
The Ca(2+) modulation in the dorsal raphe nucleus (DRN) plays an important role in sleep-wake regulation. Calmodulin-dependent kinase II (CaMKII) is an important signal-transducing molecule that is activated by Ca(2+) . This study investigated the effects of intracellular Ca(2+) /CaMKII
B L Patton et al.
Molecular biology of the cell, 4(2), 159-172 (1993-02-01)
We have visualized the distribution of autophosphorylated type II CaM kinase in neural tissue with the use of two complementary antibodies: a monoclonal antibody that binds to the alpha and beta subunits of the kinase only when they are autophosphorylated



Numéro d'article de commerce international

RéférenceGTIN
05-53304053252269264