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Merck

P2139

Poly(éthylène glycol)

greener alternative

average MN 8,000, hydroxyl

Synonyme(s) :

PEG

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A propos de cet article

Formule linéaire :
H(OCH2CH2)nOH
Numéro CAS:
UNSPSC Code:
12352104
PubChem Substance ID:
NACRES:
NA.23
MDL number:
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Nom du produit

Poly(éthylène glycol), average mol wt 8,000, powder

form

powder

Quality Segment

mol wt

average mol wt 8,000

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

solubility

water: soluble (PEG is soluble in water approximately 630 mg/ml, 20 °C)

density

1.0845 g/mL at 70 °C, 1.0689 g/mL at 90 °C

Ω-end

hydroxyl

α-end

hydroxyl

greener alternative category

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

General description

Polyethylene glycol (PEG) is a hydrophilic polymer. It can be easily synthesized by the anionic ring opening polymerization of ethylene oxide, into a range molecular weights and variety of end groups. When crosslinked into networks PEG can have high water content, forming “hydrogels”. PEG is a suitable material for biological applications because it does not trigger an immune response
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.

Application

Poly (ethylene glycol) can be used in the formulation of the drug to improve its dissolution rate and oral bioavailability.

PEG can be used for the effective isolation of edible nanoparticles (ENPs) which have excellent anti-cancer and anti-inflammatory activities. PEG is a crowding agent and forms a net-like mesh in which nanovesicles are trapped and precipitated. For example, ginger-derived ENPs are isolated using a PEG-based method which is cost-effective compared to ultracentrifugation.

PEG can be used as a precursor to synthesize degradable hydrogels for the controlled release of hydrophilic and high molecular weight pharmaceuticals.

Features and Benefits

  • Highstructural flexibility
  • Biocompatibility
  • Amphiphilicity
  • Highhydration capacity
  • Devoidof any steric hindrance


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Classe de stockage

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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