900863

2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol

≥95%

• Synonyme(s) : 3-(3-Butyn-1-yl)-3H-diazirine-3-ethanol, Hydroxyl diazirine alkyne, Probe building block
• Formule empirique (notation de Hill): C₇H₁₀N₂O
• Numéro CAS: 1450754-41-2
• Poids moléculaire : 138.17
• Numéro MDL: MFCD29918290
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 100
• Pureté: ≥95%
• Forme: liquid
• Densité: 1.08 g/mL
• Température de stockage: −20°C
• Chaîne SMILES: OCCC1(N=N1)CCC#C

Description

Application

2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and hydroxyl synthetic handle. When appended to a ligand or pharmacophore through its hydroxyl linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Autres remarques

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Design and Synthesis of Minimalist Terminal Alkyne-Containing Diazirine Photo-Crosslinkers and Their Incorporation into Kinase Inhibitors for Cell- and Tissue-Based Proteome Profiling

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable