677264

APhos

95%, solid

• Synonyme(s) : (4-(N,N-Dimethylamino)phenyl)di-tert-butyl phosphine, A-^taPhos, [4-(Dimethylamino)phenyl]bis(tert-butyl)phosphine
• Formule empirique (notation de Hill) : C₁₆H₂₈NP
• Numéro CAS: 932710-63-9
• Poids moléculaire : 265.37
• UNSPSC Code: 12352116
• PubChem Substance ID: 24885360
• NACRES: NA.22
• MDL number: MFCD09265102

Propriétés

• Nom du produit: APhos, 95%
• Quality Segment: 100
• assay: 95%
• form: solid
• reaction suitability: reaction type: Buchwald-Hartwig Cross Coupling Reaction, reaction type: Heck Reaction, reaction type: Hiyama Coupling, reaction type: Negishi Coupling, reaction type: Sonogashira Coupling, reaction type: Stille Coupling, reaction type: Suzuki-Miyaura Coupling, reagent type: ligand; reaction type: Cross Couplings
• sustainability: Sustainability features
• mp: 57-61 °C
• functional group: phosphine
• SMILES string: CN(C)c1ccc(cc1)P(C(C)(C)C)C(C)(C)C
• InChI: 1S/C16H28NP/c1-15(2,3)18(16(4,5)6)14-11-9-13(10-12-14)17(7)8/h9-12H,1-8H3
• InChI key: IQTHEAQKKVAXGV-UHFFFAOYSA-N

Description

General description

This productaligns with the Green Chemistry Principle of Catalysis. It is the APHOS ligand system for asymmetric catalysis, providing high enantioselectivity in various metal-catalyzed transformations. Click here for more information.

Application

Ligand used to prepare a palladium dichloride catalyst (678740) on treatment with PdCl₂(COD). The catalyst effectively cross-couples aryl boronic acids with heteroaryl chlorides.

Informations sur la sécurité

• Pictogrammes: GHS05
• Mot-clé: Danger
• Codes de danger: H314
• Mentions de précaution: P280 - P305 + P351 + P338 - P310
• Hazard Classifications: Skin Corr. 1B
• Classe de stockage: 8B - Non-combustible, corrosive hazardous materials
• WGK: WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable