1370270

Loratadine

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene-1-piperidinecarboxylic acid ethyl ester, Loratidine
• Empirical Formula (Hill Notation): C₂₂H₂₃N₂O₂Cl
• CAS Number: 79794-75-5
• Molecular Weight: 382.88
• NACRES: NA.24
• PubChem Substance ID: 329750256
• UNSPSC Code: 41116107
• MDL number: MFCD00672869

Properties

• grade: pharmaceutical primary standard
• agency: USP
• API family: loratadine
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: CCOC(=O)N1CC\C(CC1)=C2/c3ccc(Cl)cc3CCc4cccnc24
• InChI: 1S/C22H23ClN2O2/c1-2-27-22(26)25-12-9-15(10-13-25)20-19-8-7-18(23)14-17(19)6-5-16-4-3-11-24-21(16)20/h3-4,7-8,11,14H,2,5-6,9-10,12-13H2,1H3
• InChI key: JCCNYMKQOSZNPW-UHFFFAOYSA-N
• Gene Information: human ... HRH1(3269)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Loratadine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Loratadine Capsules
• Loratadine Chewable Tablets
• Loratadine Oral Solution
• Loratadine Orally Disintegrating Tablets
• Loratadine Tablets

Biochem/physiol Actions

Non-sedating histamine H₁-receptor antagonist.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Storage Class: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable