1131960

Cholesterol

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 3β-Hydroxy-5-cholestene, 5-Cholesten-3β-ol
• Empirical Formula (Hill Notation): C₂₇H₄₆O
• CAS Number: 57-88-5
• Molecular Weight: 386.65
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329749359
• MDL number: MFCD00003646
• Beilstein/REAXYS Number: 1915888
• eCl@ss: 25140904

Properties

• biological source: sheep
• grade: pharmaceutical primary standard
• agency: USP
• API family: cholesterol
• manufacturer/tradename: USP
• bp: 360 °C (lit.)
• mp: 147-149 °C (lit.)
• density: 1.067 g/mL at 25 °C (lit.)
• application(s): pharmaceutical; pharmaceutical; pharmaceutical (small molecule)
• format: neat
• storage temp.: −20°C
• SMILES string: CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
• InChI: 1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1
• InChI key: HVYWMOMLDIMFJA-DPAQBDIFSA-N

Description

General description

Find answers to frequently asked questions on USP products in USP FAQs.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

This USP reference standard is intended for use in specified quality tests and assays as specified in the USP compendia.
It is also used to prepare standard solution for cholesterol assay and system suitability solution for the detection of impurities in cholesterol samples using gas chromatography (GC) coupled to flame ionization detector (FID) in accordance with the United States Pharmacopeia (USP) monograph “Cholesterol”.
In addition, it is used in the detection of cholesterol impurity in omega-3 free fatty acids to prepare a standard stock solution in n-hexane for analysis by GC-FID, following USP monograph “Omega-3 Free Fatty Acids”.

Biochem/physiol Actions

Major component of all biological membranes; ~25% of total brain lipid is cholesterol.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Disclaimer

Sales restrictions may apply.

Safety Information

• Storage Class: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable