SML0130

Loxiglumide

≥97% (HPLC)

• Synonym(s): 4-[(3,4-dichlorobenzoyl)amino]-5-[(3-methoxypropyl)pentylamino]-5-oxo-pentanoic acid, CR 1505
• Empirical Formula (Hill Notation): C₂₁H₃₀Cl₂N₂O₅
• CAS Number: 107097-80-3
• Molecular Weight: 461.38
• NACRES: NA.77
• PubChem Substance ID: 329825180
• UNSPSC Code: 12352200
• MDL number: MFCD00866772
• Assay: ≥97% (HPLC)
• Form: powder
• Storage condition: desiccated

Properties

• Quality Segment: 100
• assay: ≥97% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: DMSO: ≥5 mg/mL
• storage temp.: 2-8°C
• SMILES string: CCCCCN(CCCOC)C(=O)C(CCC(O)=O)NC(=O)c1ccc(Cl)c(Cl)c1
• InChI: 1S/C21H30Cl2N2O5/c1-3-4-5-11-25(12-6-13-30-2)21(29)18(9-10-19(26)27)24-20(28)15-7-8-16(22)17(23)14-15/h7-8,14,18H,3-6,9-13H2,1-2H3,(H,24,28)(H,26,27)
• InChI key: QNQZBKQEIFTHFZ-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Loxiglumide is a CCK-A receptor antagonist

Loxiglumide is a small-molecule antagonist of the cholecystokinin receptor CCKA. Loxiglumide inhibits pancreatic secretion of digestive enzymes, and also blocks CCK-induced gastric secretions and emptying.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable