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SAB5500176

Sigma-Aldrich

Anti-SOX2 Antibody

rabbit monoclonal, SP76

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

product name

Anti-SOX-2 antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP76, affinity isolated antibody

biological source

rabbit

Quality Level

100

recombinant

expressed in proprietary host

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

SP76, monoclonal

species reactivity

human (tested)

species reactivity (predicted by homology)

frog, bovine, dog, chicken

technique(s)

immunoblotting: 1:25
immunohistochemistry: 1:100

isotype

IgG

UniProt accession no.

P48431

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

human ... SOX2(6657)

General description

Sex determining region Y-box 2 (SOX-2) is a stem cell marker and a transcription factor expressed in basal cells of the prostate, myoepithelial cells of the breast, squamous epithelium, and fetal neural cells. Recent studies show that SOX-2 is highly expressed in some human cancers such as such as prostate, lung, breast, and ovarian cancers.

Immunogen

Synthetic peptide corresponding to N-terminus of human SOX-2 protein.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Caifeng Gong et al.
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Medulloblastoma (MB) is the most common malignant pediatric brain tumor. Despite the progress of new treatments, the risk of recurrence, morbidity, and death remains important. The neuropilin-1 (NRP-1) receptor has recently been implicated in tumor progression of MB, which seems
Vinton W T Cheng et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 28(11), 2385-2396 (2022-03-22)
Despite optimal local therapy, tumor cell invasion into normal brain parenchyma frequently results in recurrence in patients with solid tumors. The aim of this study was to determine whether microvascular inflammation can be targeted to better delineate the tumor-brain interface

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