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RAB0857

Sigma-Aldrich

Mouse Ptx3 / Pentraxin-related Protein PTX3 ELISA Kit

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About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

species reactivity

mouse

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type plasma
sample type serum
sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.6 ng/mL
standard curve range: 0.614-150 ng/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

mouse ... Ptx3(19288)

General description

The antibody pair provided in this kit recognizes mouse Pentraxin-related Protein PTX3 / Pentraxin 3.
The pentraxin3 (PTX3) gene encodes for a long PTX3 protein, an acute-phase protein. PTX3 protein is a member of the pentraxin family and is present in several cells and tissues. It is observed during brain inflammatory response and seizure. PTX3 plays a role in angiogenesis, tissue remodeling, and female fertility. It promotes phagocytosis of pathogen and inhibits the phagocytosis of apoptotic cells. The antibody pair provided in this kit recognizes mouse pentraxin-related protein PTX3 / pentraxin 3.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Kit Components Also Available Separately

Product No.
Description
SDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS
  • RABSTOP3ELISA Stop Solution (Item I)SDS
  • RABWASH420X Wash Buffer (Item B)SDS

Pictograms

Corrosion
GHS05

Signal Word

Warning

Hazard Statements

H290

Precautionary Statements

P234 - P390

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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H Li et al.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 25(4), 504-510 (2018-07-03)
Pentraxin 3 (PTX3) contributes to resistance to Aspergillus infections. This study aimed to evaluate the presence of PTX3 in bronchoalveolar lavage fluid (BALF) and plasma in non-neutropenic patients with pulmonary aspergillosis. BALF (n = 211) and plasma samples (n = 307) were collected from
Hyejin Jeon et al.
Journal of neuroimmunology, 229(1-2), 63-72 (2010-08-03)
Microglia, as the phagocytes of the central nervous system, play an important role in the recognition, engulfment, and clearance of apoptotic cells and invading microbes. Proteins secreted from activated glial cells may affect microglial phagocytic activity. Secreted proteins of mixed
Ning Xu et al.
Medicine, 99(3), e18740-e18740 (2020-02-06)
To investigate the interaction between the single nucleotide polymorphism of the 3' untranslated region (3'UTR) of the pentraxin 3 (PTX3) gene, as well as environmental factors and the preeclampsia risk in a Chinese Han population.Sanger sequencing was used to analyze
Beata Kusnierz-Cabala et al.
Clinical laboratory, 59(9-10), 1003-1008 (2013-11-28)
Pentraxin 3 (PTX3) belongs to the acute phase proteins; its concentration increases significantly in the early stages of inflammation. In nearly 20% of patients with acute pancreatitis (AP) escalated inflammation leads to the development of severe forms of the disease.
Hrishikesh S Kulkarni et al.
JCI insight, 5(17) (2020-08-05)
BACKGROUNDThe complement system plays a key role in host defense but is activated by ischemia/reperfusion injury (IRI). Primary graft dysfunction (PGD) is a form of acute lung injury occurring predominantly due to IRI, which worsens survival after lung transplantation (LTx).
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