Skip to Content
Merck
All Photos(1)

Documents

M6514

Sigma-Aldrich

3-(Trimethoxysilyl)propyl methacrylate

≥97%

Synonym(s):

Silane A174, [3-(Methacryloyloxy)propyl]trimethoxysilane

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
H2C=C(CH3)CO2(CH2)3Si(OCH3)3
CAS Number:
Molecular Weight:
248.35
Beilstein:
1952435
EC Number:
MDL number:
UNSPSC Code:
47101511
PubChem Substance ID:
NACRES:
NA.56

Assay

≥97%

form

liquid

refractive index

n20/D 1.431 (lit.)

bp

190 °C (lit.)

density

1.045 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

CO[Si](CCCOC(=O)C(C)=C)(OC)OC

InChI

1S/C10H20O5Si/c1-9(2)10(11)15-7-6-8-16(12-3,13-4)14-5/h1,6-8H2,2-5H3

InChI key

XDLMVUHYZWKMMD-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

3-(Trimethoxysilyl)propyl methacrylate (TMSPMA) is a hydrophobic monomer. The presence of an additional functional group of acrylate facilitates TMSPMA for grafting polymerization on plastic surfaces. 3-(Trimethoxysilyl)propyl methacrylate undergoes first-order kinetic polymerization to form polyTMSPMA, which is a moisture stable polymer.

Application

3-(Trimethoxysilyl)propyl methacrylate has been used in the following applications:
  • Isoelectric focusing can lead to pH gradient formation resulting in the swelling or shrinking of gel casts. This can be prevented by using 3-(Trimethoxysilyl)propyl methacrylate to link polyacrylamide gels to glass plates covalently.
  • In situ hybridization using 3-(Trimethoxysilyl)propyl methacrylate along with poly-L-lysine is a faster and durable method to attach cells, microscopic sections, and total organs to slides/other glass surfaces.
  • 3-(Trimethoxysilyl)propyl methacrylate is also used in the preparation of organic/inorganic hybrid nanomaterials.

Packaging

A product Information sheet is supplied which describes procedures for using this product.

related product

Product No.
Description
Pricing

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

197.6 °F - closed cup

Flash Point(C)

92 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Ke Liu et al.
Journal of colloid and interface science, 365(1), 289-295 (2011-10-04)
Thermoplastics have been increasingly used for fabricating microfluidic devices because of their low cost, mechanical/biocompatible attributes, and well-established manufacturing processes. However, there is sometimes a need to integrate such a device with components made from other materials such as polydimethylsiloxane
ATRP of 3-(triethoxysilyl)propyl methacrylate and preparation of ?stable? gelable block copolymers
Ming Xiong
European Polymer Journal, 44, 3835-3841 (2008)
Sean Brahim et al.
Biomacromolecules, 4(5), 1224-1231 (2003-09-10)
An amphiphilic hydrogel of poly(2-hydroxyethyl methacrylate) cross-linked with tetraethyleneglycol diacrylate (TEGDA) was synthesized to contain the hydrophobic monomer 3-(trimethoxy-silyl) propyl methacrylate (PMA) and the pH-responsive, hydrophilic monomer N',N'-dimethylaminoethyl methacrylate (DMAEMA). The gels were separately loaded with two biomolecular probes, insulin
Method for attachment of microscopic preparations on glass for in situ hybridization, PRINS and in situ PCR studies.
H M Dyanov et al.
BioTechniques, 18(5), 822-824 (1995-05-01)
Bozhen Zhang et al.
Journal of materials chemistry. B, 9(35), 7196-7204 (2021-07-23)
Label-free cell sorting devices are of great significance for biomedical research and clinical therapeutics. However, current platforms for label-free cell sorting cannot achieve continuity and selectivity simultaneously, resulting in complex steps and limited reliability. Here, an immunoaffinity-based cell catch-transport-release thermo-chemo-mechanical

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service