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M6385

Sigma-Aldrich

Methyl cellulose

viscosity: 25 cP

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About This Item

CAS Number:
9004-67-5
MDL number:
MFCD00081763
UNSPSC Code:
12352201
PubChem Substance ID:
24897005
NACRES:
NA.25
Pricing and availability is not currently available.

Quality Level

200

form

powder

color

white to off-white

viscosity

20-30 cP, 2 % in water(20 °C)

SMILES string

[*]OC[C@H]1O[C@@H](O[C@@H]2[C@@H](CO[*])O[C@@H](O[*])[C@H](O[*])[C@H]2O[*])[C@H](O[*])[C@@H](O[*])[C@@H]1O[*]

InChI key

YLGXILFCIXHCMC-JHGZEJCSSA-N

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General description

Methyl cellulose (MC) is a simple derivative of cellulose.[1]

Application

Methyl cellulose has been used:
  • as a supplement for culturing multicellular spheroids of SH-SY5Y cells[2]
  • as a supplement for culturing tumor cell spheroids[3]
  • to generate and study the rheological behavior of aqueous mullite-albumin-methylcellulose systems[4]

Biochem/physiol Actions

Methyl cellulose (MC) acts as a laxative and is hydrophilic. It has therapeutic effects against constipation, irritable bowel syndrome, and diverticulosis due to its bulk-forming and stool softening properties. MC has the potential to treat patients with ileostomies and colostomies. It may also be used as a stabilizer and emulsifier.[5] MC is a component of eye drops and contact lens solutions.[6]

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000316160
WXBF3015V
WXBF1126V
WXBF2357V
SLCN8031

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Methylcellulose
Kieth H.
xPharm: The Comprehensive Pharmacology Reference, 1-3 (2007)
Rheological behavior of aqueous mullite-albumin-methylcellulose systems
Sandoval M, et al.
Ceramics International, 43(9) (2017)
Eyedrops and ointments
Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions, 220-221 (2016)
Methylcellulose, a cellulose derivative with original physical properties and extended applications
Nasatto P L, et al.
Polymers, 7(5), 777-803 (2015)
Maria Chiara Lionetti et al.
Journal of clinical medicine, 9(8) (2020-08-14)
Melanoma is one of the most aggressive and highly resistant tumors. Cell plasticity in melanoma is one of the main culprits behind its metastatic capabilities. The detailed molecular mechanisms controlling melanoma plasticity are still not completely understood. Here we combine
View All Related Papers

Questions

1–2 of 2 Questions  

  1. Can I know the Mw range?

    1 answer

    1. The average molecular weight is 17000 Daltons.

      Helpful?

  2. What is the degree of substitution of this material?

    1 answer

    1. The degree of substitution for this product ranges from 1.6 to 1.9. The percent of substitution is 27.5 - 31.5 %.

      Helpful?

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