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M5757

Sigma-Aldrich

Maleic acid sodium salt

~99%

Synonym(s):

cis-Butenedioic acid, Toxilic acid

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About This Item

Linear Formula:
C4H3O4Na
CAS Number:
3105-55-3
Molecular Weight:
138.05
EC Number:
221-461-6
MDL number:
MFCD00070246
UNSPSC Code:
12352106
PubChem Substance ID:
24897040
NACRES:
NA.77

Assay

~99%

SMILES string

OC(/C=C\C([O-])=O)=O.[Na+]

InChI

1S/C4H4O4.Na/c5-3(6)1-2-4(7)8;/h1-2H,(H,5,6)(H,7,8);/q;+1/p-1/b2-1-;

InChI key

VRVKOZSIJXBAJG-ODZAUARKSA-M

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Biochem/physiol Actions

Maleic acid is a component of cosmetics, fragrances and has industrial applications. It is also a potent nephrotoxin and is implicated to induce glycosuria, aminoaciduria and Fanconi syndrome.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000260469
0000260813
0000260471
0000260813
0000260471

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Mei-Ling Hou et al.
Molecules (Basel, Switzerland), 21(3), 367-367 (2016-03-22)
Maleic acid has been shown to be used as a food adulterant in the production of modified starch by the Taiwan Food and Drug Administration. Due to the potential toxicity of maleic acid to the kidneys, this study aimed to
Shirley A Aguirre et al.
Toxicologic pathology, 40(5), 797-806 (2012-05-04)
Maleic acid was formulated in 0.7% saline and injected intravitreally in rabbits in order to evaluate ocular safety and tolerability. Maleic acid was formulated within a narrow pH range (2-3), administered in a fixed volume (100 µl), and concentrations ranged
Jing-hang Xu et al.
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 20(7), 512-516 (2012-10-10)
To evaluate the efficacy and safety of entecavir (ETV) maleate versus ETV in Chinese patients with hepatitis B e antigen (HBeAg)-negative chronic hepatitis B (CHB). This was a randomized, double-blind, double-dummy, controlled, multicenter study. Patients were randomly assigned to receive
Ke Chen et al.
Dalton transactions (Cambridge, England : 2003), 41(17), 5391-5400 (2012-04-05)
A series of enantiomerically pure 1,2-diester substituted P,N-ligands incorporating two chiral carbons in the backbone were generated in high yields and high stereoselectivity from acetylenedicarboxylate via initial hydrophosphination using diphenylphosphine followed by hydroamination with various primary and secondary amines. The
Kun Liu et al.
Applied and environmental microbiology, 79(3), 1044-1047 (2012-12-04)
HbzF from Pseudomonas alcaligenes NCIMB 9867 was purified to homogeneity as a His-tagged protein and likely a dimer by SDS-PAGE and gel filtration. This protein was demonstrated to be a novel maleylpyruvate hydrolase, catalyzing direct hydrolysis of maleylpyruvate to maleate
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