Skip to Content
Merck

Skip To

M3781

6α-Methylprednisolone 21-hemisuccinate sodium salt

synthetic, ≥98.00% (TLC), Prednisolone derivative, lyophilized powder

Synonym(s):

6α-Methylprednisolone sodium succinate, MPSL, 6α-Methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione 21-hemisuccinate

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice

About This Item

Linear Formula:
C26H33O8Na
CAS Number:
Molecular Weight:
496.53
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
EC Number:
219-156-8
MDL number:
Assay:
≥98.00% (TLC)
Form:
lyophilized powder
Pricing and availability is not currently available.
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


Product Name

6α-Methylprednisolone 21-hemisuccinate sodium salt, lyophilized powder

biological source

synthetic

Quality Segment

sterility

non-sterile

assay

≥98.00% (TLC)

form

lyophilized powder

technique(s)

toxicology assay: suitable

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

shipped in

ambient

storage temp.

room temp

SMILES string

[Na+].C[C@H]1CC2C3CC[C@](O)(C(=O)COC(=O)CCC([O-])=O)[C@@]3(C)C[C@H](O)C2[C@@]4(C)C=CC(=O)C=C14

InChI

1S/C26H34O8.Na/c1-14-10-16-17-7-9-26(33,20(29)13-34-22(32)5-4-21(30)31)25(17,3)12-19(28)23(16)24(2)8-6-15(27)11-18(14)24;/h6,8,11,14,16-17,19,23,28,33H,4-5,7,9-10,12-13H2,1-3H3,(H,30,31);/q;+1/p-1/t14-,16-,17-,19-,23+,24-,25-,26-;/m0./s1

InChI key

FQISKWAFAHGMGT-SGJOWKDISA-M

Gene Information

human ... NR3C1(2908)

Application

6α-methylprednisolone 21-hemisuccinate sodium salt has been used to investigate glucocorticoid-induced osteonecrosis under hypoxic conditions in the MC3T3-E1 osteoblast cell line using a cell cytotoxicity assay, flow cytometry and western blotting.

Biochem/physiol Actions

Glucocorticoid with slightly longer half-life than that of prednisolone.

Physical form

Lyophilized containing ~5% phosphate buffer salts.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
H4881P86501435003
form

lyophilized powder

form

powder

form

powder

form

-

assay

≥98.00% (TLC)

assay

≥90% (HPLC)

assay

≥97%

assay

-

technique(s)

toxicology assay: suitable

technique(s)

-

technique(s)

-

technique(s)

-

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

-

storage temp.

room temp

storage temp.

−20°C

storage temp.

room temp

storage temp.

-

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

solubility

chloroform: methanol (1:1): 50 mg/mL, clear, colorless

solubility

-


pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Carc. 2 - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library



Questions

  1. How long is product M3781 good for once it is reconstituted in water?

    1 answer
    1. There is no available information on the duration for which the product remains viable once reconstituted, as it was not tested for this purpose.

      Helpful?

Reviews

No rating value

Active Filters