Skip to Content
Merck
All Photos(1)

Documents

GE38152103011150

Sera-Mag Magnetic Oligo(dt) particles

Cytiva 38152103011150, 1 μm avg. part. size, suspension (1% Solids)

Sign Into View Organizational & Contract Pricing


About This Item

UNSPSC Code:
41115700
NACRES:
NA.56

ligand

(carboxylate modified particles)

form

suspension (1% Solids)

packaging

pkg of 1 mL

manufacturer/tradename

Cytiva 38152103011150

concentration

10 mg/mL

avg. part. size

1 μm

shipped in

wet ice

storage temp.

2-8°C

General description

Sera-Mag SpeedBeads and Sera-Mag Carboxylate-Modified Magnetic Particles combine a fast magnetic response time and high binding capacity with a large surface area, high sensitivity, stability, physical integrity, and fast reaction kinetics. Covalent coupling of biomolecules such as proteins and nucleic acids to carboxyl groups on the surface is easily accomplished using our standard coupling technology. The core of the particle is made by a free radical emulsion polymerization of styrene and acid monomer. One (Sera-Mag) or two (Sera-Mag SpeedBeads) layers of magnetite are then coated onto this core, while the surface is modified to minimize non-specific binding of proteins.

Application

Sera-Mag SpeedBeads and Sera-Mag Carboxylate-Modified Magnetic Particles typical application uses include sample preparation, proteomics, nucleic acid isolation, and immunoassay applications.
Sera-Mag Magnetic Olido(dt) particles can be used for convenient isolation and extraction of mRNA from a variety of sources for downstream applications such as RT-PCR, cDNA library construction, cDNA microarrays, affinity purification, primer extension and subtractive hybridization.
Sera-Mag SpeedBeads and Sera-Mag Carboxylate-Modified Magnetic Particles typical application uses include sample preparation, proteomics, nucleic acid isolation, and immunoassay applications.

Features and Benefits

Sera-Mag SpeedBeads and Sera-Mag Carboxylate-Modified Magnetic Particles allow convenient covalent coupling of target molecules.

  • Carboxylic groups on the surface permit easy covalent coupling to biomolecules of interest using convenient carbodiimide chemistry.
  • Different levels of hydrophobicity/hydrophilicity available.
  • Available in Sera-Mag SpeedBeads and original Sera-Mag versions.
  • Excellent sensitivity and low nonspecific binding for greater accuracy.
  • Fast Magnetic Response Times and Stable Physical Integrity.
  • Very high, specific poly A+ binding capacity ensures maximum extraction of mRNA.
  • Covalently bound oligo(dT)14 prevents leaching from the particle surface.
  • Encapsulation means no exposed iron and minimized interference with downstream enzymatic applications.
  • Uniform, nominal 1 μm diameter provides high surface area and excellent lot-to-lot reproducibility.
Sera-Mag SpeedBeads and Sera-Mag Carboxylate-Modified Magnetic Particles allow convenient covalent coupling of target molecules.

  • Carboxylic groups on the surface permit easy covalent coupling to biomolecules of interest using convenient carbodiimide chemistry.
  • Different levels of hydrophobicity/hydrophilicity available.
  • Available in Sera-Mag SpeedBeads and original Sera-Mag versions.
  • Excellent sensitivity and low nonspecific binding for greater accuracy.
  • Fast Magnetic Response Times and Stable Physical Integrity

Storage and Stability

Unless otherwise stated, refrigerate (2-8 °C) product when not in use but do not freeze. Store upright and keep bottle tightly sealed. Mix product with gentle inversion by hand, roller or vortex mixer.

Analysis Note

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

Legal Information

Sera-Mag is a trademark of Cytiva

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

De novo transcriptome assembly of the mountain fly Drosophila nigrosparsa using short RNA-seq reads.
Arthofera W, et al.
Molecular Ecology Resources null
Sequencing, Annotation, and Characterization of the Influenza Ferret Infectome.
Leon A J, et al.
Journal of Virology, 87(4), 1957-1966 (2013)
Computational identification and systematic classification of novel cytochrome P450 genes in Salvia miltiorrhiza.
Chen H, et al.
PLoS ONE, 9(12), e115149-e115149 (2014)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service