E2634

Ergosta-5,7,9(11),22-tetraen-3β-ol

~96% (HPLC)

• Synonym(s): Dehydroergosterol
• Empirical Formula (Hill Notation): C₂₈H₄₂O
• CAS Number: 516-85-8
• Molecular Weight: 394.63
• NACRES: NA.77
• PubChem Substance ID: 24894479
• UNSPSC Code: 12352200
• MDL number: MFCD00083319
• Assay: ~96% (HPLC)

Properties

• assay: ~96% (HPLC)
• Quality Segment: 200
• storage temp.: −20°C
• SMILES string: [H][C@@]1(CC[C@@]2([H])C3=CC=C4C[C@@H](O)CC[C@]4(C)C3=CC[C@]12C)[C@H](C)\C=C\[C@H](C)C(C)C
• InChI: 1S/C28H42O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-10,14,18-20,22,24-25,29H,11-13,15-17H2,1-6H3/b8-7+/t19-,20+,22-,24+,25-,27-,28+/m0/s1
• InChI key: QSVJYFLQYMVBDR-CMNOFMQQSA-N

Description

General description

Ergosta-5,7,9(11),22-tetraen-3β-ol is an analogue of ergosterol. It comprises of three conjugated double bonds in a steroid ring system. Ergosta-5,7,9(11),22-tetraen-3β-ol possesses anti-inflammatory property. It is used as a cholesterol reporter.

Application

A fluorescent cholesterol analog useful as a probe in membrane research.

Ergosta-5,7,9(11),22-tetraen-3β-ol has been used to examine the acyltransferase activity of lecithin:cholesterol acyltransferase (LCAT). It has also been used for liposome preparation.

Safety Information

• pictograms: GHS08
• signalword: Warning
• hcodes: H351,H373
• pcodes: P201 - P308 + P313
• Hazard Classifications: Carc. 2 - STOT RE 2
• Storage Class: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable