D6382
N,N-Dimethylglycine hydrochloride
≥98%, suitable for ligand binding assays
Synonym(s):
N,N-Dimethylaminoacetic acid hydrochloride
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About This Item
Linear Formula:
(CH3)2NCH2COOH · HCl
CAS Number:
Molecular Weight:
139.58
Beilstein:
3910578
EC Number:
MDL number:
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26
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Product Name
N,N-Dimethylglycine hydrochloride,
Assay
≥98%
Quality Level
form
powder
technique(s)
ligand binding assay: suitable
color
white
mp
189-194 °C (lit.)
SMILES string
Cl.CN(C)CC(O)=O
InChI
1S/C4H9NO2.ClH/c1-5(2)3-4(6)7;/h3H2,1-2H3,(H,6,7);1H
InChI key
FKASAVXZZLJTNX-UHFFFAOYSA-N
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Biochem/physiol Actions
N,N-Dimethylglycine (DMG) is a natural N-methylated glycine that is used in comparative analysis with other N-methylated glycines such as sarcosine and βine. N,N-Dimethylglycine is used in the development of glycine-based ionic liquids and emulsifiers. N,N-Dimethylglycine is potentially useful as a biomarker of protein degradation in COPD patients. DMG is used as a substrate to identify, differentiate and characterize amino acid methyltransferase(s).
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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The aim of this study was to develop a prodrug of ubiquinol-10 (UqH-10), the active form of ubiquinone-10 (Uq-10), for oral delivery. Bioavailability of UqH-10 is hampered by its high susceptibility to oxidation and water-insolubility. We prepared three novel N,N-dimethylglycine
Baljit K Ubhi et al.
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There is a paucity of biomarkers for chronic obstructive pulmonary disease (COPD). Metabolomics were applied to a defined COPD patient cohort from the ECLIPSE study (Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points). Results were correlated with accepted biomarkers
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Chen SY, Lai MC, Lai SJ, Lee YC.
Applied Microbiology, 191, 735-743 (2009)
A J Hoorn
Mutation research, 222(4), 343-350 (1989-04-01)
Dimethylglycine (DMG) and the chemically related amino acids glycine, sarcosine (monomethylglycine) and betaine (trimethylglycine) were tested in Salmonella typhimurium strain TA100 after treatment with sodium nitrite under acidic conditions using a modified Ames Salmonella/microsome assay as reported by Colman et
Jing-Fang Zhu et al.
The journal of physical chemistry. B, 116(1), 113-119 (2011-12-14)
The experimental and theoretical enthalpies of formation of several structural-similar glycine-based sulfate/bisulfate amino acid ionic liquids including glycine sulfate (Gly(2)SO(4), 1), glycine bisulfate (GlyHSO(4), 2), N,N-dimethylglycine sulfate ([DMGly](2)SO(4), 3), N,N-dimethylglycine bisulfate ([DMGly]HSO(4), 4), N,N-dimethylglycine methyl ester sulfate ([DMGlyC(1)](2)SO(4), 5), N,N-dimethylglycine
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