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A4638

Azathioprine

synthetic (organic), ≥98%, DNA/RNA synthesis disruptor, powder

Synonym(s):

6-(1-Methyl-4-nitroimidazol-5-yl)thiopurine

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About This Item

Empirical Formula (Hill Notation):
C9H7N7O2S
CAS Number:
446-86-6
Molecular Weight:
277.26
NACRES:
NA.77
PubChem Substance ID:
57653853
UNSPSC Code:
12352202
EC Number:
207-175-4
MDL number:
MFCD00069203
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Product Name

Azathioprine, ≥98%

biological source

synthetic (organic)

Quality Segment

assay

≥98%

form

powder

solubility

1 M NH4OH: 20 mg/mL, clear to slightly hazy

storage temp.

−20°C

SMILES string

Cn1cnc(c1Sc2ncnc3[nH]cnc23)[N+]([O-])=O

InChI

1S/C9H7N7O2S/c1-15-4-14-7(16(17)18)9(15)19-8-5-6(11-2-10-5)12-3-13-8/h2-4H,1H3,(H,10,11,12,13)

InChI key

LMEKQMALGUDUQG-UHFFFAOYSA-N

Gene Information

human ... PPAT(5471)

Biochem/physiol Actions

Has shown promise in treatment of alopecia areata (autoimmune hair loss), with no difference in effectiveness between genders.

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This Item
1046001A4660M6875
Azathioprine ≥98%

Sigma-Aldrich

A4638

Azathioprine

Azathioprine United States Pharmacopeia (USP) Reference Standard

USP

1046001

Azathioprine

6-Thioguanine Hybri-Max™, 50 ×, γ-irradiated, lyophilized powder, BioXtra, suitable for hybridoma

Sigma-Aldrich

A4660

6-Thioguanine

2-Mercaptopurine ≥95%, crystalline

Sigma-Aldrich

M6875

2-Mercaptopurine

description

≥98%

description

United States Pharmacopeia (USP) Reference Standard

description

Hybri-Max™, 50 ×, γ-irradiated, lyophilized powder, BioXtra, suitable for hybridoma

description

≥95%, crystalline

biological source

synthetic (organic)

biological source

-

biological source

synthetic (organic)

biological source

-

assay

≥98%

assay

-

assay

~98%

assay

≥95%

Gene Information

human ... PPAT(5471)

Gene Information

human ... PPAT(5471)

Gene Information

human ... IMPDH1(3614), IMPDH2(3615)

Gene Information

-

Quality Level

100

Quality Level

-

Quality Level

200

Quality Level

100

form

powder

form

-

form

lyophilized powder

form

crystalline

solubility

1 M NH4OH: 20 mg/mL, clear to slightly hazy

solubility

-

solubility

1 M NaOH: 50 mg/mL, clear to slightly hazy

solubility

1 M NH4OH: 50 mg/mL, clear to slightly hazy, yellow to brown

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Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

PPE (personal protective equipment)

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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    Certificates of Analysis (COA)

    Lot/Batch Number
    WXBF9286V
    077F0565
    085K1209
    074K1466
    050H0871

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