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For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
84510
Saponin
used as non-ionic surfactant
Synonym(s):
glycosides, saponins
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About This Item
biological source
plant (Quillaya)
Quality Segment
form
powder
composition
Sapogenin, 8-25%
greener alternative product characteristics
Less Hazardous Chemical Syntheses
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
technique(s)
HPLC: suitable, protein quantification: suitable
impurities
≤20% sulphated ash
CMC
0.001-0.01%
solubility
water: 1 g/10 mL, clear to hazy, yellow to brown
density
1.015-1.020 g/mL at 20 °C (5% in H2O)(lit.)
greener alternative category
SMILES string
C[C@]1(CCC23COC4([C@H]2C1)CC[C@@H]5[C@]6(CC[C@@H](C(C6CC[C@]5([C@@]4(C[C@H]3O)C)C)(C)C)O[C@H]7[C@@H]([C@H]([C@H](CO7)O[C@H]8[C@@H]([C@H]([C@@H](CO8)O)O)O)O[C@@H]9[C@@H]([C@H]([C@@H]([C@H](O9)CO)O)O)O)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O[C@@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)C)C=O
InChI
1S/C58H94O27/c1-52(2)29-7-11-55(5)30(8-12-58-31-15-53(3,22-62)13-14-57(31,23-77-58)32(64)16-56(55,58)6)54(29,4)10-9-33(52)82-50-46(85-51-45(40(71)37(68)27(19-61)80-51)84-49-43(74)39(70)36(67)26(18-60)79-49)44(83-48-42(73)38(69)35(66)25(17-59)78-48)28(21-76-50)81-47-41(72)34(65)24(63)20-75-47/h22,24-51,59-61,63-74H,7-21,23H2,1-6H3/t24-,25-,26-,27-,28+,29?,30-,31+,32-,33+,34+,35-,36-,37-,38+,39+,40+,41-,42-,43-,44+,45-,46-,47+,48-,49-,50+,51+,53-,54+,55-,56+,57?,58?/m1/s1
InChI key
MAEBCGDGGATMSC-OSHGGGOQSA-N
General description
Beyond their structural uniqueness, saponins play essential roles in biochemical processes, acting as secondary metabolites that facilitate protein penetration through cell membranes. Studies indicate their amphipathic nature and potential as hemolytic agents, contributing to their utility in immunoassays by stimulating the Th1 immune response and cytotoxic T-lymphocyte production. In cell biology, saponins find applications as nonionic surfactants, influencing cellular processes and interactions.
Moreover, saponins serve as promising components in vaccine research, functioning as adjuvants that can activate the mammalian immune system. This property, combined with their ability to solubilize low-density lipoproteins and regulate cholesterol concentration in micelles, makes saponins versatile and valuable in multidisciplinary research areas, including biochemical and cell biology research.
Application
- as a wetting agent to study its effects on the floatability of six plastics
- to permeabilize washed neutrophils for immunofluorescence
- as a supplement in phosphate buffer saline (PBS) for immunocytochemistry
Biochem/physiol Actions
Features and Benefits
- Suitable for Biochemical and Cell Biology research
- Can be used with HPLC and Protein Quantification
- High purity product for research applications
Other Notes
1 of 1
This Item | |||
|---|---|---|---|
| form powder | form - | form - | form solid |
| technique(s) HPLC: suitable, protein quantification: suitable | technique(s) HPLC: suitable, protein quantification: suitable | technique(s) HPLC: suitable, LC/MS: suitable, protein quantification: suitable | technique(s) - |
| CMC 0.001-0.01% | CMC 0.001-0.01% | CMC - | CMC - |
| impurities ≤20% sulphated ash | impurities - | impurities - | impurities ≤10% ash |
| Quality Level 300 | Quality Level 200 | Quality Level 200 | Quality Level 100 |
| density 1.015-1.020 g/mL at 20 °C (5% in H2O)(lit.) | density 1.015-1.020 g/mL at 20 °C (5% in H2O)(lit.) | density - | density - |
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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How can I determine the shelf life / expiration / retest date of this product?
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How is shipping temperature determined? And how is it related to the product storage temperature?
1 answer-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
Helpful?
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what is the molecular weight of product: 84510
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The molecular weight of this product is not determined. However, historical data suggests this material contains saponins with a molecular weight range of 1400-2000 Daltons. The actual molecular weight is dependent upon the number of sugar residues attached to the core.
Helpful?
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Qual è la composizione del prodotto, o almeno da dove è derivato?
1 answer-
This product is saponin from quillaya bark. This triterpene saponine consists of Quillaicacid (structure kindly find enclosed below) combined with saccharide chains. Hydrolysis yields Quillaic acid, glacturonic acid, glucuronic acid and galactose (from Roempp's Chemical Encyclopedia).
Please see the sample Certificate of Origin for more information:
https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COO/Q12/84510-BULKSLCF7866.pdfHelpful?
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