137256

MES monohydrate

EMPROVE^® EVOLVE

• Synonym(s): MES, 2-(N-Morpholino)ethanesulfonic acid, 4-Morpholineethanesulfonic acid monohydrate
• Linear Formula: C6H13NO4S · H2O
• CAS Number: 145224-94-8
• Molecular Weight: 213.25
• UNSPSC Code: 12161700
• Beilstein/REAXYS Number: 6350956
• MDL number: MFCD00149409

Properties

• biological source: synthetic
• Quality Segment: 400
• product line: EMPROVE^® EVOLVE
• form: powder
• technique(s): cell culture | mammalian: suitable, pH adjustment: suitable
• impurities: Endotoxin, microbial, and trace metals, tested
• pH: 5.5-6.7
• useful pH range: 5.5-6.7
• pKa (25 °C): 6.1
• pKa: 6.1
• mp: >300 °C (lit), >300 °C (lit.)
• suitability: suitable for manufacturing use
• foreign activity: Cytotoxicity, DNase, NICKase, RNase, and Protease; tested
• storage temp.: 2-30°C
• SMILES string: O.OS(=O)(=O)CCN1CCOCC1
• InChI: 1S/C6H13NO4S.H2O/c8-12(9,10)6-3-7-1-4-11-5-2-7;/h1-6H2,(H,8,9,10);1H2
• InChI key: MIIIXQJBDGSIKL-UHFFFAOYSA-N

Description

Application

MES is a biological buffer often referred to as a “Good′s” buffer .The pKa of MES is 5.96 which makes MES an ideal candidate for cell culture media and protein based buffer formulations to maintain a stable environment in solution. MES is considered to be non-toxic to culture cell lines, highly water soluble and provides high solution clarity.MES is used in cell culture media, biopharmaceutical buffer formulations (both upstream and downstream), and diagnostic reagents. MES based buffers are used in purification bioprocesses of antibodies, peptides, proteins, blood components and growth factors.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• WGK: WGK 3