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AB5087

Anti-Melanocyte Stimulating Hormone α Antibody

serum, Chemicon®

Synonym(s):

alpha-MSH, POMC, Pro-opiomelanocortin, Corticotropin-lipotropin precursor

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, RIA
Citations:
66
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biological source

sheep

Quality Level

300

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity (predicted by homology)

mammals

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable, radioimmunoassay: suitable

NCBI accession no.

NM_000939.2, NM_001035256.1

UniProt accession no.

P01189

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... POMC(5443)

Immunogen

MSH conjugated with bovine thyroglobulin.

Application

Anti-Melanocyte Stimulating Hormone Antibody, α detects level of Melanocyte Stimulating Hormone & has been published & validated for use in IH, RIA.
Immunohistochemistry: 1:10,000-1:50,000 on 4% paraformaldehyde fixed tissue.

RIA: 1:250,000-1:300,000.

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
CNS Control of Metabolism

Hormones & Receptors

Biochem/physiol Actions

Specific for alpha-melanocyte stimulating hormone (aMSH), C-terminal.

Physical form

Sheep Serum. Liquid. Contains no preservative.
Unpurified

Preparation Note

Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Analysis Note

Control
Hypothalamus

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item
M0939SAB2500826HPA063644
Anti-Melanocyte Stimulating Hormone α Antibody serum, Chemicon®

Sigma-Aldrich

AB5087

Anti-Melanocyte Stimulating Hormone α Antibody

Anti-α-MSH antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution

Sigma-Aldrich

M0939

Anti-α-MSH antibody produced in rabbit

Anti-Proopiomelanocortin/POMC antibody produced in goat affinity isolated antibody, buffered aqueous solution

Sigma-Aldrich

SAB2500826

Anti-Proopiomelanocortin/POMC antibody produced in goat

Anti-POMC antibody produced in rabbit Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody

Sigma-Aldrich

HPA063644

Anti-POMC antibody produced in rabbit

antibody form

serum

antibody form

IgG fraction of antiserum

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

Quality Level

300

Quality Level

200

Quality Level

100

Quality Level

100

biological source

sheep

biological source

rabbit

biological source

goat

biological source

rabbit

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

technique(s)

immunohistochemistry: suitable, radioimmunoassay: suitable

technique(s)

ELISA: 1:4,000, microarray: suitable

technique(s)

immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable

technique(s)

immunohistochemistry: 1:5000- 1:10000

shipped in

wet ice

shipped in

dry ice

shipped in

dry ice

shipped in

wet ice

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Maja Cigrovski Berkovic et al.
Neuroendocrinology, 99(2), 75-84 (2014-04-02)
Although previously considered rare, recent epidemiological studies have revealed that the incidence (3.6/100,000) and prevalence (35/100,000) of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) has increased over the past few decades. Despite the progress in the understanding of GEP-NET molecular biology, there is
Fumihiko Maekawa et al.
Frontiers in synaptic neuroscience, 5, 7-7 (2013-10-10)
We previously reported that the type 2 diabetic Goto-Kakizaki (GK) rats at young adult ages (6-12 weeks) exhibited increased visceral fat mass and hyperleptinemia, due to hyperphagia caused primarily by neuropeptide Y (NPY) overexpression in the hypothalamic arcuate nucleus. Later
B E Grayson et al.
Endocrinology, 151(4), 1622-1632 (2010-02-24)
The hypothalamic melanocortin system, which controls appetite and energy expenditure, develops during the third trimester in primates. Thus, maternal nutrition and health may have a profound influence on the development of this system. To study the effects of chronic maternal
View All Related Papers

Global Trade Item Number

SKUGTIN
AB508704053252736599

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