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Sigma-Aldrich

1-Cyclohexyl-2-pyrrolidone

High-boiling aprotic solvent., 99%

Synonym(s):

1-Cyclohexyl-2-pyrrolidinone, CHP, N-Cyclohexyl-2-pyrrolidinone, N-Cyclohexyl-2-pyrrolidone, N-Cyclohexylpyrrolidinone, N-Cyclohexylpyrrolidone

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About This Item

Empirical Formula (Hill Notation):
C10H17NO
CAS Number:
6837-24-7
Molecular Weight:
167.25
Beilstein:
121832
EC Number:
229-919-7
MDL number:
MFCD00003191
UNSPSC Code:
12352100
PubChem Substance ID:
24853888
NACRES:
NA.22

vapor pressure

0.05 mmHg ( 25 °C)

Quality Level

100

Assay

99%

refractive index

n20/D 1.499 (lit.)

bp

154 °C/7 mmHg (lit.)

density

1.007 g/mL at 25 °C (lit.)

SMILES string

O=C1CCCN1C2CCCCC2

InChI

1S/C10H17NO/c12-10-7-4-8-11(10)9-5-2-1-3-6-9/h9H,1-8H2

InChI key

PZYDAVFRVJXFHS-UHFFFAOYSA-N

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Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H302 + H312,H314

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 1

Flash Point(F)

285.8 °F - closed cup

Flash Point(C)

141 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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E Q Lawson et al.
The Journal of biological chemistry, 259(5), 2910-2912 (1984-03-10)
The compound N-cyclohexyl-2-pyrrolidone contains a substantial apolar region as well as a peptide bond-like moiety. This solvent, therefore, provides a useful model for protein interiors. Under certain conditions of temperature and salt concentration, cyclohexylpyrrolidone forms a two-phase system with water.
Extraction of aromatics from petroleum naphtha reformate by a 1-cyclohexyl-2-pyrrolidone/ethylene carbonate mixed solvent.
Radwan GM, et al.
Industrial & Engineering Chemistry Research, 36(2), 414-418 (1997)
P J Becci et al.
Fundamental and applied toxicology : official journal of the Society of Toxicology, 4(4), 587-593 (1984-08-01)
Teratogenesis studies were performed in rats and rabbits given N-cyclohexyl-2-pyrrolidone, an aprotic solvent used in chemical processing. Dosages of 0, 15, 50, 150, or 500 mg N-cyclohexyl-2-pyrrolidone/kg body wt/day were administered by gavage to groups of 25 pregnant Sprague-Dawley rats
Karina Milagros Cui et al.
ACS applied materials & interfaces, 3(7), 2300-2308 (2011-06-10)
The facile preparation of poly (N-vinyl carbazole) (PVK) and multiwalled carbon nanotubes (MWNTs) solution and conjugated polymer network (CPN) nanocomposite film is described. The stable solutions of PVK/MWNT were prepared in mixed solvents by simple sonication method, which enabled successful
Lothar Schwarz et al.
Journal of forensic sciences, 52(3), 649-655 (2007-04-26)
A new method for enhancement of ninhydrin or 1,8-diazafluoren-9-one (DFO)-treated latent fingerprints on thermal paper will be described. Most thermosensitive surfaces of thermal paper become dark when treated with DFO or ninhydrin petroleum ether (NPB) solution. This effect minimizes contrast

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