SML2503

Pellitorine

≥97% (HPLC)

• Synonyme(s) : (2E,4E)-N-(2-Methylpropyl)-2,4-decadienamide, (2E,4E)-N-Isobutyl-2,4-decadienamide, 2E,4E-Decadienoic acid N-isobutylamide, trans-Pellitorin, trans-Pellitorine
• Formule empirique (notation de Hill) : C₁₄H₂₅NO
• Numéro CAS: 18836-52-7
• Poids moléculaire : 223.35
• UNSPSC Code: 51111800
• NACRES: NA.77
• MDL number: MFCD01735995
• Assay: ≥97% (HPLC)
• Form: powder
• Storage condition: desiccated

Propriétés

• assay: ≥97% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: −20°C
• SMILES string: N(CC(C)C)C(=O)\C=C\C=C\CCCCC
• InChI: 1S/C14H25NO/c1-4-5-6-7-8-9-10-11-14(16)15-12-13(2)3/h8-11,13H,4-7,12H2,1-3H3,(H,15,16)/b9-8+,11-10+
• InChI key: MAGQQZHFHJDIRE-BNFZFUHLSA-N

Description

Biochem/physiol Actions

ACAT inhibitor; α-Glucosidase inhibitor; anti-inflammatory;

Pellitorine is an α-Glucosidase inhibitor isolated from the roots of Piper Nigrum that exhibit anti-diabetic, anti-cancer, anti-bacterial and anti-inflammatory properties. Pellitorine is an ACAT (Acyl-CoA cholesteryl acyl transferase) inhibitor that inhibits cholesterol esterification in HepG2 cells. Also pellitorine exhibit potent larvicide activity in mosquito by Inhibition of gene expression encoding V-type H+-ATPase and aquaporine 4. Some new research suggests that anti-adipogenic activity of pellitorine depends on TRPV1.

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable