SML1101

Nedocromil sodium

≥98% (HPLC)

• Synonyme(s) : 9-Ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano[3,2-g]quinoline-2,8-dicarboxylic acid sodium salt, Nedocromil disodium salt
• Formule empirique (notation de Hill): C₁₉H₁₅NO₇ · 2 Na
• Numéro CAS: 69049-74-7
• Poids moléculaire : 415.30
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.77

Propriétés

• Pureté: ≥98% (HPLC)
• Forme: powder
• Conditions de stockage: desiccated
• Couleur: , white to beige to brown
• Solubilité: H₂O: 20 mg/mL, clear
• Température de stockage: 2-8°C
• InChI: 1S/C19H17NO7.2Na/c1-3-5-9-16-10(13(21)7-12(18(23)24)20(16)4-2)6-11-14(22)8-15(19(25)26)27-17(9)11;;/h6-8H,3-5H2,1-2H3,(H,23,24)(H,25,26);;/q;2*+1/p-2
• Clé InChI: JQEKDNLKIVGXAU-UHFFFAOYSA-L

Description

Actions biochimiques/physiologiques

Nedocromil is a mast cell stabilizer and anti-inflammatory and anti-allergic drug. Nedocromil inhibits the degranulation of mast cells, and prevents the activation of and mediator release from a variety of inflammatory cell types. Nedocromil inhibits release of histamine, leukotriene C4, and prostaglandin D2, but has no antihistamine, bronchodilator, or corticosteroid activity itself.

Nedocromil is considered to be more effective in treating asthma compared to a placebo.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable