SAB4300122

Anti-phospho-TYK2 (pTyr¹⁰⁵⁴) antibody produced in rabbit

affinity isolated antibody

• Synonyme(s) : Anti-JTK1 antibody produced in rabbit, Anti-tyrosine kinase 2 antibody produced in rabbit
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: ~140 kDa
• Espèces réactives: human, rat, mouse
• Concentration: 1 mg/mL
• Technique(s): western blot: 1:500-1:1000
• Isotype: IgG
• Séquence immunogène: (H-E-YP-Y-R)
• Numéro d'accès NCBI: NP_003322.3
• Numéro d'accès UniProt: P29597
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: phosphorylation (pTyr1054)
• Informations sur le gène: human ... TYK2(7297)

Description

Immunogène

Peptide sequence around phosphorylation site of tyrosine 1054 (H-E-Y(p)-Y-R), according to the protein TYK2.

Caractéristiques et avantages

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Description de la cible

TYK2 encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.

Forme physique

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable