SAB1403982

Monoclonal Anti-INS antibody produced in mouse

clone 7C8, purified immunoglobulin, buffered aqueous solution

• Synonyme(s) : ILPR, IRDN
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: mouse
• Conjugué: unconjugated
• Forme d'anticorps: purified immunoglobulin
• Type de produit anticorps: primary antibodies
• Clone: 7C8, monoclonal
• Forme: buffered aqueous solution
• Poids mol.: antigen ~1.65 kDa
• Espèces réactives: human
• Technique(s): indirect ELISA: suitable
• Isotype: IgG3κ
• Numéro d'accès NCBI: NM_000207
• Numéro d'accès UniProt: P01308
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... INS(3630)

Description

Description générale

After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5′ region and with the IGF2 gene at the 3′ region. (provided by RefSeq)

Immunogène

KLH-conjugated human Proinsulin peptide (NP_000198, 48 a.a. ~ 62 a.a)

Sequence
CFFYTPKTRREAEDLQ

Forme physique

Solution in phosphate buffered saline, pH 7.4

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable