S7531
Anti-Staphylococcal α-Toxin antibody produced in rabbit
whole antiserum
Synonyme(s) :
Anti-α-Hemolysin
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About This Item
Produits recommandés
Source biologique
rabbit
Niveau de qualité
Conjugué
unconjugated
Forme d'anticorps
whole antiserum
Type de produit anticorps
primary antibodies
Clone
polyclonal
Poids mol.
antigen 33 kDa
Contient
15 mM sodium azide
Espèces réactives
Staphylococcus aureus
Conditionnement
antibody small pack of 25 μL
Technique(s)
dot blot: 1:20,000
indirect ELISA: 1:50,000
Conditions d'expédition
dry ice
Température de stockage
−20°C
Modification post-traductionnelle de la cible
unmodified
Description générale
Staphylococcal α toxin, a water soluble 33kD single polypeptide, is a cytotoxic agent secreted by Staphylococcus aureus. This protein has membrane damaging properties and accounts for erythrocyte lysis. Hence it is also referred to as lethal hemolytic toxin or α-hemolysin . Anti-staphylococcal α-toxin antibody can be used for studies of the toxin-membrane interaction. Rabbit anti-staphylococcal α-toxin antibody reacts specifically with staphylococcal α-toxin but not with staphylococcal enterotoxin A, cholera toxin or pseudomonas exotoxin A.
Immunogène
α-toxin (α-hemolysin) from Staphylococcus aureus
Application
Anti-staphylococcal α-toxin antibody can be used in indirect ELISA (1:50,000) and dot blot immunoassay (1: 20,000).
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Enzyme-linked immunosorbent assay (1 paper)
Enzyme-linked immunosorbent assay (1 paper)
Qualité
The antiserum has been treated to remove lipoproteins.
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
nwg
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
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Les clients ont également consulté
Shi-Jie Wan et al.
Frontiers in chemistry, 10, 877469-877469 (2022-04-19)
The emergence of antibiotic resistance in Staphylococcus aureus has necessitated the development of innovative anti-infective agents acting on novel targets. Alpha-hemolysin (Hla), a key virulence factor of S. aureus, is known to cause various cell damage and death. In this
Alicia Lacoma et al.
Toxins, 13(2) (2021-02-11)
Staphylococcus aureus is a commensal and frequent colonizer of the upper respiratory tract. When mechanical ventilation disrupts natural defenses, S. aureus is frequently isolated from the lower airways, but distinguishing between colonization and infection is difficult. The objectives of this
S Forti et al.
European journal of biochemistry, 181(3), 767-773 (1989-05-15)
alpha-Toxin, a lethal hemolytic toxin secreted by Staphylococcus aureus, forms ionic channels of large size in lipid membranes. To investigate the mechanism of channel assembly we have studied the kinetics of pore formation on small unilamellar vesicles. We have used
Olivia A Todd et al.
mBio, 10(3) (2019-06-06)
Candida albicans and Staphylococcus aureus are among the most prevalent nosocomial pathogens that are responsible for severe morbidity and mortality, even with appropriate treatment. Using a murine model of polymicrobial intra-abdominal infection (IAI), we have previously shown that coinfection with
María Belén Mestre et al.
Autophagy, 6(1), 110-125 (2010-01-30)
Staphylococcus aureus is a pathogen that causes serious infectious diseases eventually leading to septic and toxic shock. Classically S. aureus has been considered an extracellular pathogen, but cumulative evidence indicates that it invades cells and replicates intracellularly leading to staphylococcal
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..
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