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R3280

Sigma-Aldrich

Monoclonal Anti-RPA/p70 antibody produced in mouse

~1.5 mg/mL, clone 2H10, purified immunoglobulin, buffered aqueous solution

Synonyme(s) :

Monoclonal Anti-REPA1, Monoclonal Anti-RF-A, Monoclonal Anti-RP-A, Monoclonal Anti-RPA70, Monoclonal Anti-hSSB, Monoclonal Anti-replication protein A1, 70kDa

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About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

mouse

Conjugué

unconjugated

Forme d'anticorps

purified immunoglobulin

Type de produit anticorps

primary antibodies

Clone

2H10, monoclonal

Forme

buffered aqueous solution

Poids mol.

antigen ~70 kDa

Espèces réactives

human

Concentration

~1.5 mg/mL

Technique(s)

immunocytochemistry: suitable
western blot: 1-2 μg/mL using HeLa total cell extract

Isotype

IgG1

Numéro d'accès UniProt

P27694

Conditions d'expédition

dry ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... RPA1(6117)

Immunogène

purified human RPA/p70.

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Forme physique

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Yan Wang et al.
Neurotoxicity research, 25(2), 193-207 (2013-09-03)
Dopamine β-hydroxylase (DBH) and norepinephrine (NE) transporter (NET) are the noradrenergic phenotypes for their functional importance to noradrenergic neurons. It is known that in vivo N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP4) treatment induces degeneration of noradrenergic terminals by interacting with NET and depleting intracellular
M A Serrano et al.
Oncogene, 32(19), 2452-2462 (2012-07-17)
Homologous recombination (HR) and nonhomologous end joining (NHEJ) are two distinct DNA double-stranded break (DSB) repair pathways. Here, we report that DNA-dependent protein kinase (DNA-PK), the core component of NHEJ, partnering with DNA-damage checkpoint kinases ataxia telangiectasia mutated (ATM) and
Emanuela Grassilli et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 19(14), 3820-3831 (2013-06-05)
Evasion from chemotherapy-induced apoptosis due to p53 loss strongly contributes to drug resistance. Identification of specific targets for the treatment of drug-resistant p53-null tumors would therefore increase the effectiveness of cancer therapy. By using a kinase-directed short hairpin RNA library
M K Kenny et al.
The Journal of biological chemistry, 265(13), 7693-7700 (1990-05-05)
Human single-stranded DNA binding protein (human SSB) is a multisubunit protein containing polypeptides of 70, 34, and 11 kDa that is required for SV40 DNA replication in vitro. In this report we identify the functions of the SSB and its

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