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M8770

Sigma-Aldrich

Anti-Mouse IgG1 (heavy chain specific) antibody produced in goat

affinity isolated antibody, lyophilized powder

Synonyme(s) :

Anti-Mouse Igg1, Heavy Chain Specific Secondary Antibody, Heavy Chain Specific Secondary Antibody - Anti-Mouse IgG1 (heavy chain specific) antibody produced in goat

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About This Item

Numéro MDL:
MFCD00162649
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.46

Source biologique

goat

Niveau de qualité

300

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

secondary antibodies

Clone

polyclonal

Forme

lyophilized powder

Technique(s)

Ouchterlony double diffusion: suitable

Température de stockage

2-8°C

Modification post-traductionnelle de la cible

unmodified

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Description générale

Immunoglobulin IgG is a glycoprotein antibody with two light chains and a pair of identical heavy chains.

Immunogène

Mouse IgG1 (myeloma protein)

Application

Anti-Mouse IgG1 (heavy chain specific) antibody is suitable for use in immunoelectrophoresis and Ouchterlony double diffusion. The antibody may also be used in immunoblot .
Anti-Mouse IgG1 (heavy chain specific) antibody produced in goat has been used in immunohistochemistry and enzyme-linked immunosorbent assay (ELISA)

Actions biochimiques/physiologiques

Digestion of IgG by papain results in the generation of fragment antigen-binding (Fab). Pepsin digestion of IgG results in fragment crystallizable (fc). IgG1 is most abundant of IgG types and its deficiency results in hypogammaglobulinemia.

Forme physique

Lyophilized from 0.01 M phosphate buffered saline, pH 7.2.

Reconstitution

Reconstitute with 0.135 M sodium chloride.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

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A H Schrijvers et al.
Cancer research, 53(18), 4383-4390 (1993-09-15)
Using viable cells of a human head and neck squamous cell carcinoma (HNSCC) cell line as immunogen, we developed monoclonal antibody (MAb) U36. Immunohistochemical examination revealed distinct surface labeling of MAb U36 with normal human squamous epithelium and squamous cell
The combined effect of mesenchymal stem cells and resveratrol on type 1 diabetic neuropathy
Wang C, et al.
Experimental and Therapeutic Medicine, 17(5), 3555-3563 (2019)
J Pass et al.
Scandinavian journal of immunology, 58(3), 298-305 (2003-09-03)
The urokinase receptor (uPAR) is a glycolipid-anchored cell surface glycoprotein that plays a central role in extracellular proteolysis during tissue remodeling processes including cancer invasion. Furthermore, uPAR is found on the surface of both dendritic cells (DCs) and T cells
Min-Kyung Sung et al.
Molecular biology of the cell, 27(17), 2642-2652 (2016-07-08)
Ribosome assembly is an essential process that consumes prodigious quantities of cellular resources. Ribosomal proteins cannot be overproduced in Saccharomyces cerevisiae because the excess proteins are rapidly degraded. However, the responsible quality control (QC) mechanisms remain poorly characterized. Here we
Fei Wang et al.
Oncology letters, 18(2), 1888-1894 (2019-08-20)
Src homologous and collagen (SHC) SH2-binding protein 1 (SHCBP1) is a member of the SHC family, and is overexpressed in numerous types of cancer. In addition, apoptosis serves an important role in the development of cancer. The purpose of this
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