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Merck

M6199

Minimum Essential Medium Eagle

StableCell, Alpha modification, with stable glutamine and sodium bicarbonate, without nucleosides, liquid, sterile-filtered, suitable for cell culture

Synonyme(s) :

MEM

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UNSPSC Code:
12352207
NACRES:
NA.75
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Nom du produit

Milieu essentiel minimum d′Eagle, With stable glutamine and sodium bicarbonate, without ribonucleosides and deoxyribonucleosides, liquid, sterile-filtered, suitable for cell culture

Quality Segment

sterility

sterile-filtered

form

liquid

technique(s)

cell culture | mammalian: suitable

impurities

Endotoxin, tested

components

Earle’s salts (5% CO2): yes
NaHCO3: yes
stable glutamine: yes
phenol red: yes
L-glutamine: no
glucose: yes
HEPES: no
Hanks’ salts (2% CO2): no
sodium pyruvate: yes

shipped in

ambient

storage temp.

2-8°C

General description

This α-MEM differs from the original formula, because it is supplemented with L-alanyl-L-glutamine dipeptide. Glutamine is notoriously unstable in cell culture. This dipeptide provides a more stable form of glutamine for use in cell cultures.

Legal Information

StableCell is a trademark of Sigma-Aldrich Co. LLC


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Classe de stockage

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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Simona Giunta et al.
The Journal of cell biology, 190(2), 197-207 (2010-07-28)
The signaling cascade initiated in response to DNA double-strand breaks (DSBs) has been extensively investigated in interphase cells. Here, we show that mitotic cells treated with DSB-inducing agents activate a "primary" DNA damage response (DDR) comprised of early signaling events
Pasqualino de Antonellis et al.
PloS one, 6(9), e24584-e24584 (2011-09-21)
Through negative regulation of gene expression, microRNAs (miRNAs) can function as oncosuppressors in cancers, and can themselves show altered expression in various tumor types. Here, we have investigated medulloblastoma tumors (MBs), which arise from an early impairment of developmental processes
Barbara Zonta et al.
Neuron, 69(5), 945-956 (2011-03-09)
The axon initial segment (AIS) is critical for the initiation and propagation of action potentials. Assembly of the AIS requires interactions between scaffolding molecules and voltage-gated sodium channels, but the molecular mechanisms that stabilize the AIS are poorly understood. The



Numéro d'article de commerce international

RéférenceGTIN
M6199-500ML04061834060765