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M1778

Sigma-Aldrich

Mucine from porcine stomach

Type III, bound sialic acid 0.5-1.5 %, partially purified powder

Synonyme(s) :

MUC

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About This Item

Numéro CAS:
84082-64-4
Numéro CE :
282-010-7
Numéro MDL:
MFCD00131629
Code UNSPSC :
12352202
Nomenclature NACRES :
NA.61

Source biologique

Porcine stomach

Type

Type III

Forme

partially purified powder

Composition

bound sialic acid, 0.5-1.5%

Technique(s)

microbiological culture: suitable

Solubilité

NaOH: soluble 20 mg/mL

Température de stockage

2-8°C

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Description générale

Mucins or mucus glycoproteins are the main macromolecular components of mammalian mucus. It was also used in a study to evaluate the sputum smears concentrated by cyto-centrifugation for detection of acid-fast bacilli.

Application

Mucin from porcine stomach was used in studies on the binding site of the galactose-specific agglutinin PA-IL from Pseudomonas aeruginosa.

Actions biochimiques/physiologiques

Mucus forms the protective cover for all epithelial surfaces. The major structural component of mucus is gel-forming mucins. The mucus layer covering the intestinal epithelium has the MUC2 mucin as its central molecule. MUC2 is produced by goblet cells.

Notes préparatoires

Prepared according to the method of Glenister, et al., for use in complex growth media for dental plaque bacteria.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

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Kenny C Mok et al.
mBio, 11(6) (2020-12-10)
The beneficial human gut bacterium Akkermansia muciniphila provides metabolites to other members of the gut microbiota by breaking down host mucin, but most of its other metabolic functions have not been investigated. A. muciniphila strain MucT is known to use
Lihui Feng et al.
Proceedings of the National Academy of Sciences of the United States of America, 117(5), 2622-2633 (2020-01-24)
Human gut microbiota development has been associated with healthy growth but understanding the determinants of community assembly and composition is a formidable challenge. We cultured bacteria from serially collected fecal samples from a healthy infant; 34 sequenced strains containing 103,102
Anastasia Matthies et al.
Applied and environmental microbiology, 74(15), 4847-4852 (2008-06-10)
The metabolism of isoflavones by gut bacteria plays a key role in the availability and bioactivation of these compounds in the intestine. Daidzein and genistein are the most common dietary soy isoflavones. While daidzein conversion yielding equol has been known
Helen Rose et al.
The Journal of antimicrobial chemotherapy, 63(3), 502-510 (2009-01-21)
The Burkholderia cepacia complex (Bcc) species are important opportunistic pathogens with intrinsic antibiotic resistance. They are also well known as contaminants of disinfectants, yet their biocide susceptibility has not been studied in detail. We investigated Bcc biocide susceptibility and correlated
Leyuan Li et al.
Microbiome, 8(1), 33-33 (2020-03-13)
Human-targeted drugs may exert off-target effects or can be repurposed to modulate the gut microbiota. However, our understanding of such effects is limited due to a lack of rapid and scalable assay to comprehensively assess microbiome responses to drugs. Drugs
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