E2250

Ellagic acid

≥95% (HPLC), powder, from tree bark

• Synonyme(s) : 4,4′,5,5′,6,6′-Hexahydroxydiphenic acid 2,6,2′,6′-dilactone, Alizarin Yellow, Benzoaric acid, Elagostasine, Eleagic acid, Gallogen, Lagistase
• Formule empirique (notation de Hill): C₁₄H₆O₈
• Numéro CAS: 476-66-4
• Poids moléculaire : 302.19
• Numéro Beilstein : 47549
• Numéro CE : 207-508-3
• Numéro MDL: MFCD00006914
• Code UNSPSC : 12352205
• ID de substance PubChem : 24894460
• Nomenclature NACRES : NA.77

Propriétés

• Source biologique: tree bark
• Pureté: ≥95% (HPLC)
• Forme: powder
• Durée de conservation: 5 yr
• Solubilité: 1 M NaOH: 10 mg/mL
• Application(s): metabolomics; vitamins, nutraceuticals, and natural products
• Chaîne SMILES: Oc1cc2C(=O)Oc3c(O)c(O)cc4C(=O)Oc(c1O)c2-c34
• InChI: 1S/C14H6O8/c15-5-1-3-7-8-4(14(20)22-11(7)9(5)17)2-6(16)10(18)12(8)21-13(3)19/h1-2,15-18H
• Clé InChI: AFSDNFLWKVMVRB-UHFFFAOYSA-N
• Informations sur le gène: human ... CSK(1445) , DYRK1A(1859) , GSK3B(2932) , SRC(6714) ; rat ... Lyn(81515) , Syk(25155)

Description

Description générale

Ellagic acid is a naturally occurring phenolic acid in many fruits and vegetables, as a secondary plant metabolite. It is commonly found in green tea, pomegranate, strawberries, blackberries, raspberries, and walnuts.

Application

Ellagic acid has been used:

• to study the metabolism of dietary phenolic acids by Lactobacillus plantarum CECT 748T
• as a potential substrate for the high production of Lactobacillus plantarum tannase
• as a standard in the study to examine the phenolic components and anti-oxidant activity of nettle
• to study the links between dietary ellagic acid and epigenetic modulation of adipogenesis

Actions biochimiques/physiologiques

Ellagic acid has been found to exhibit antioxidant activity by virtue of having an inhibitory effect on the oxidation of low-density lipoproteins. This makes them have a cardioprotective effect on humans. In addition, it shows anticarcinogenic, antifibrotic, antiplasmodial, apoptotic, and chemopreventive activities as well.

Commonly occurring plant polyphenol, inhibitor of glutathione S-transferase. Used for the assay of factor XIIa in plasma. Contact activation in blood coagulation.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves