C2105

Z-Val-Ala-Asp fluoromethyl ketone

≥90% (TLC), Caspase-1 inhibitor, powder

• Synonyme(s) : Z-VAD-FMK, Non-methylated
• Formule empirique (notation de Hill) : C₂₁H₂₈FN₃O₇
• Numéro CAS: 161401-82-7
• Poids moléculaire : 453.46
• UNSPSC Code: 12352209
• PubChem Substance ID: 329774926
• NACRES: NA.77
• MDL number: MFCD03452883
• Assay: ≥90% (TLC)
• Form: powder

Propriétés

• Nom du produit: Z-Val-Ala-Asp fluoromethyl ketone, powder, ≥90% (TLC)
• Quality Segment: 200
• assay: ≥90% (TLC)
• form: powder
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)CF
• InChI: 1S/C21H28FN3O7/c1-12(2)18(25-21(31)32-11-14-7-5-4-6-8-14)20(30)23-13(3)19(29)24-15(9-17(27)28)16(26)10-22/h4-8,12-13,15,18H,9-11H2,1-3H3,(H,23,30)(H,24,29)(H,25,31)(H,27,28)/t13-,15-,18-/m0/s1
• InChI key: SUUHZYLYARUNIA-YEWWUXTCSA-N

Description

Biochem/physiol Actions

Non-methylated competitive and irreversible inhibitor of caspase-1, as well as other caspases, which can be used directly with purified enzymes. It does not require esterase to hydrolyze the O-methyl ester like the cell-permeable form, Z-Val-Ala-Asp(OMe) fluoromethyl ketone (Product Code V-116).

Features and Benefits

This compound is featured on the Caspases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)