C1688
Monoclonal Anti-C-Reactive Protein antibody produced in mouse
clone CRP-8, ascites fluid
Synonyme(s) :
Anti-CRP
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About This Item
Produits recommandés
Source biologique
mouse
Niveau de qualité
Conjugué
unconjugated
Forme d'anticorps
ascites fluid
Type de produit anticorps
primary antibodies
Clone
CRP-8, monoclonal
Poids mol.
antigen 24 kDa
Contient
15 mM sodium azide
Espèces réactives
human
Technique(s)
dot blot: suitable
indirect ELISA: 1:40,000
western blot: 1:200
Isotype
IgG1
Numéro d'accès UniProt
Conditions d'expédition
dry ice
Température de stockage
−20°C
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
human ... CRP(1401)
Description générale
C-reactive protein (CRP) is a member of the pentraxin family of proteins and synthesized by the liver. It is also known as PTX1. The CRP gene is mapped to human chromosome 1q23.2.
Spécificité
The antibody recognizes an epitope located on the 24 kDa subunit of denatured and reduced CRP. It does not cross-react with human serum amyloid P component (SAP), human haptoglobin, human α1-acid glycoprotein, human IgG, and CRP from Limulus.
Immunogène
human C-reactive protein.
Application
- It has been used in immunoblotting assay, to identify monomeric CRP.
- In time-resolved fluorometric assay.
Monoclonal Anti-C-Reactive Protein antibody produced in mouse is suitable for the following:
- dot blot analysis
- indirect ELISA at a working dilution of 1:40,000
- western blotting at a working dilution of 1:200
Actions biochimiques/physiologiques
C-reactive protein (CRP) shows essential scavenging and metabolic activity and is also associated with defence mechanism. It activates the complement pathway by binding to calcium-dependent exogenous and autologous molecules containing phosphocholine (PC). It may have pathogenic effects and is a practical prognostic marker in patients with hepatocellular carcinoma (HCC). The CRP diagnostic value is higher for acute pyelonephritis than lower urinary tract infection. Thus, it helps in differentiating between upper and lower urinary tract infection. It is considered best for predicting the risk of cardiovascular disease..
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
12 - Non Combustible Liquids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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Les clients ont également consulté
Birgit Fendl et al.
Scientific reports, 11(1), 6996-6996 (2021-03-28)
There is increasing evidence that C-reactive protein (CRP) can mediate inflammatory reactions following the transformation of functionally inert pentameric CRP (pCRP) into its structural isoform pCRP* and into monomeric CRP (mCRP). This conversion can occur on the membranes of apoptotic
C-reactive protein specifically enhances platelet-activating factor-induced inflammatory activity in vivo.
Sato A, et al.
European Journal of Pharmacology, 745, 46-51 (2014)
The effect of C-reactive protein deposition on myocardium with ischaemia-reperfusion injury in rats.
Se Jin Oh et al.
Interactive cardiovascular and thoracic surgery, 25(2), 260-267 (2017-05-06)
We evaluated the effect of monomeric C-reactive protein (CRP) deposition on areas at risk (AAR) of myocardium with ischaemia-reperfusion injury. Myocardial ischaemia-reperfusion injury model was produced by ligation of the left anterior descending coronary artery for 45 min followed by 45 min
Travis W Hein et al.
Circulation research, 114(1), 92-100 (2013-10-22)
Studies in cultured endothelium implicate that lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) or Fcγ receptor II (CD32) contributes to the proatherogenic effects of C-reactive protein (CRP). However, the identity of the receptors linking to deleterious actions of CRP in vasomotor
Eun Na Kim et al.
Journal of chest surgery, 54(1), 9-16 (2021-03-27)
The deposition of monomeric C-reactive protein (mCRP) in the myocardium aggravates ischemia-reperfusion injury (IRI) and myocardial infarction. Ischemic preconditioning (IPC) is known to protect the myocardium against IRI. We evaluated the effects of IPC on myocardium upon which mCRP had
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..
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