C0563

Cardiolipin sodium salt from bovine heart

≥97% (TLC), lyophilized powder

• Synonyme(s) : Diphosphatidylglycerol
• UNSPSC Code: 12352211
• NACRES: NA.25
• MDL number: MFCD00071040

Propriétés

• biological source: bovine heart
• Quality Segment: 200
• assay: ≥97% (TLC)
• form: lyophilized powder
• lipid type: phosphoglycerides
• shipped in: ambient
• storage temp.: −20°C

Description

General description

Cardiolipin is localized in the inner membrane of mitochondria. It contains 18 carbon atoms, 3-phosphatidyl groups connected via a glycerol bridge. Cardiolipin is an important component of ATP synthase enzyme.

Application

Cardiolipin sodium salt from bovine heart has been used:

• as a phospholipid standard in thin layer chromatography for the quantification of total mitochondrial lipids of Neurospora crassa(89)
• as an internal standard in reverse phase high performance liquid chromatography (RP-HPLC) for quantification of bacterial lipid extracts(90)
• as an antigen to evaluate IgM reaction in systemic lupus erythematosus (SLE) patients(91)

Biochem/physiol Actions

Cardiolipin is a mitochondrial phospholipid that is found in mammalian tissues in low concentrations. It is often a membrane component. Inhibits cell attachment of fibronectin, vitronectin and Type I collagen.

Packaging

packaged under argon

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)